41593-58-2 Usage
Description
BORANE-DIPHENYLPHOSPHINE COMPLEX is a versatile chemical compound that plays a significant role in various chemical reactions and processes due to its unique properties and reactivity. It is widely utilized in the field of organic chemistry for its ability to participate in a range of reactions, making it a valuable asset for researchers and chemists.
Uses
Used in Organic Chemistry:
BORANE-DIPHENYLPHOSPHINE COMPLEX is used as a reactant for nucleophilic addition reactions, where it acts as an anion to facilitate the process. This application is crucial for the synthesis of various organic compounds and contributes to the development of new materials and pharmaceuticals.
Used in Catalytic Dehydrogenation:
In the presence of ruthenium bidentate phosphine complexes, BORANE-DIPHENYLPHOSPHINE COMPLEX is used as a catalyst for dehydrogenation reactions. This application is essential in the production of various chemicals and materials, as well as in the synthesis of pharmaceuticals.
Used in Deprotonation Reactions:
BORANE-DIPHENYLPHOSPHINE COMPLEX serves as a reagent in deprotonation reactions, where it helps to remove a proton (H+) from a molecule. This process is vital in the synthesis of various organic compounds and contributes to the development of new materials and pharmaceuticals.
Used in Catalytic Coupling with Alkynyl Bromides:
BORANE-DIPHENYLPHOSPHINE COMPLEX is used as a catalyst in the coupling reactions with alkynyl bromides, leading to the formation of new carbon-carbon bonds. This application is crucial in the synthesis of complex organic molecules and the development of new materials and pharmaceuticals.
Used in Catalyst-free Staudinger Ligation:
For indirect 18F-radiolabeling, BORANE-DIPHENYLPHOSPHINE COMPLEX is used in a catalyst-free Staudinger ligation process. This application is significant in the field of medical imaging, as it allows for the development of radiolabeled compounds that can be used in diagnostic procedures.
Used in the Preparation of Chiral Phosphine-Phosphite Bidentate Ligands:
BORANE-DIPHENYLPHOSPHINE COMPLEX is utilized in the preparation of chiral phosphine-phosphite bidentate ligands with a biphenyl backbone. These ligands are essential in asymmetric catalysis, which is a crucial process in the synthesis of enantiomerically pure compounds, often found in pharmaceuticals.
Used in Reactions with Frustrated Lewis Pair Combinations:
BORANE-DIPHENYLPHOSPHINE COMPLEX is used in reactions involving frustrated Lewis pair combinations of group 14 triflates and sterically hindered nitrogen bases. This application is significant in the development of new catalytic systems and the synthesis of various organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 41593-58-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,5,9 and 3 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 41593-58:
(7*4)+(6*1)+(5*5)+(4*9)+(3*3)+(2*5)+(1*8)=122
122 % 10 = 2
So 41593-58-2 is a valid CAS Registry Number.
41593-58-2Relevant articles and documents
Ni-Catalyzed enantioselective reductive arylcyanation/cyclization of: N -(2-iodo-aryl) acrylamide
Dong, Kaiwu,Ren, Xinyi,Shen, Chaoren,Wang, Guangzhu
, p. 1135 - 1138 (2022/02/03)
A Ni/(S,S)-BDPP-catalyzed intramolecular Heck cyclization of N-(2-iodo-aryl) acrylamide with 2-methyl-2-phenylmalononitrile was developed to give oxindoles with good enantioselectivities. We found that utilizing such an electrophilic cyanation reagent cou
Direct conversion of sec-phosphine oxides to sec-phosphine-boranes using BH3
Yamada, Masatoshi,Goto, Mitsutaka,Yamano, Mitsuhisa
, (2021/02/22)
An effective and mild synthetic method for secondary phosphine-boranes from secondary phosphine oxides was developed. The slow addition of borane-tetrahydrofuran to a solution of secondary phosphine oxides at ambient temperature gave secondary phosphine-boranes with high yield. The use of air-sensitive secondary phosphines, which are common substrates for secondary phosphine-borane syntheses, is avoided in this mild process. Moreover, generation of by-products, such as secondary hydroxy-phosphine-boranes, is also minimized.
Michael Addition of P-Nucleophiles to Conjugated Nitrosoalkenes
Naumovich, Yana A.,Ioffe, Sema L.,Sukhorukov, Alexey Yu.
, p. 7244 - 7254 (2019/06/14)
A general approach to various α-phosphorus-substituted oximes (β-oximinoalkyl-substituted phosphonates, phosphine oxides, phosphine-borane complexes, and phosphonium salts) was developed. The strategy exploits hitherto unknown Michael addition of PH-containing compounds (diphenylphosphine oxide, diisopropyl phosphite, phosphine-borane complexes, and triphenylphosphonium bromide) to unstable conjugated nitrosoalkenes, which are generated in situ from corresponding nitrosoacetals. The resulting α-phosphorus-substituted oximes can be considered as useful P-, N-, and O-ligands for catalysis and precursors to valuable β-aminophosphonates.
