4124-31-6 Usage
Description
Trichloroacetic anhydride is a colorless liquid that serves as an efficient derivatization reagent, producing stable derivatives with a higher mass fragmentation pattern and lower volatility compared to other anhydrides such as trifluoroacetic anhydride (TFAA) or heptafluorobutyric anhydride (HFBA). It is known for its interaction with compounds like thymidine 5′-phosphate in the presence of tertiary amines.
Uses
Used in Chemical Synthesis:
Trichloroacetic anhydride is used as a reagent in organometallic reactions and for the synthesis of oxadiazole-containing 5-lipoxygenase activating protein inhibitors. Its unique properties make it a valuable component in the development of various chemical compounds and pharmaceuticals.
Used in Derivatization:
Trichloroacetic anhydride is utilized as a derivatization reagent, enhancing the stability, mass fragmentation pattern, and reducing the volatility of the resulting derivatives. This application is particularly useful in the analysis and identification of various compounds in chemical and pharmaceutical research.
Used in Pharmaceutical Research:
In the pharmaceutical industry, trichloroacetic anhydride plays a crucial role in the synthesis of specific protein inhibitors, which can be used for the development of new drugs targeting various diseases and conditions. Its efficiency in producing stable derivatives makes it a preferred choice for researchers in drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 4124-31-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,2 and 4 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4124-31:
(6*4)+(5*1)+(4*2)+(3*4)+(2*3)+(1*1)=56
56 % 10 = 6
So 4124-31-6 is a valid CAS Registry Number.
InChI:InChI=1/C4Cl6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10
4124-31-6Relevant articles and documents
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Wasserman,Wharton
, p. 1411,1413 (1960)
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Method of preparing a benzofuran or benzothiophene compound
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, (2008/06/13)
The invention concerns a novel method for preparing a benzofuran or benzothiophene compound by cyclizing an aromatic compound bearing a side-chain comprising at least two carbon atoms, one of the carbon atoms being bound to the benzene cycle by an oxygen or sulphur atom, the other carbon atom is in carboxylic form and a formyl radical in ortho position relative to said chain. The inventive method is characterised in that it consists in cyclizing the latter in the presence of an efficient amount of a carbonate base in a medium comprising a carboxylic acid anhydride and optionally an organic solvent.
Hydroxy protection groups
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, (2008/06/13)
The present invention concerns a method for preparing unprotected hydroxy compounds or acylated derivatives thereof by conversion of silyl alkyl-protected hydroxy compounds. The invention also relates to novel intermediates useful in the method and for other purposes.