4114-28-7Relevant articles and documents
Tuning the electrical and optical properties of dinuclear ruthenium complexes for near infrared optical sensing
Xun, Shidi,LeClair, Gaetan,Zhang, Jidong,Chen, Xin,Gao, Jian Ping,Wang, Zhi Yuan
, p. 1697 - 1700 (2006)
Redox-active dinuclear ruthenium complexes with various 1,2-dicarbonylhydrazido (DCH) ligands are designed and prepared to have intense absorption in the near-infrared region for potential optical sensing in aqueous media, as demonstrated for sensing hydrogen peroxide in this study.
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Nozaki et al.
, p. 45 (1967)
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Photooxidation mechanism of nitrogen-containing compounds at TiO2/H2O interfaces: An experimental and theoretical examination of hydrazine derivatives
Waki, Kunio,Zhao, Jincai,Horikoshi, Satoshi,Watanabe, Natsuko,Hidaka, Hisao
, p. 337 - 343 (2000)
The photocatalytic oxidation of oxalyldihydrazide, N,N'- bis(hydrazocarbonyl)hydrazide, N,N'-bis(ethoxycarbonyl)hydrazide, malonyldihydrazide, N-malonyl-bis[(N'-ethoxycarbonyl)hydrazide] was examined in aqueous TiO2 dispersions under UV illumination. The photomineralization of nitrogen and carbon atoms in the substrates into N2 gas, NH4/+ (and/or NO3/-) ions, and CO2 gas was determined by HPLC and GC analysis. The formation of carboxylic acid intermediates also occurred in the photooxidation process. The photocatalytic mechanism is discussed on the basis of the experimental results, and with molecular orbital (MO) simulation of frontier electron density and point charge. Substrate carbonyl groups readily adsorb on the TiO2 surface, and the bonds between carbonyl group carbon atoms and adjacent hydrazo group nitrogen atoms are cleaved predominantly in the initial photooxidation process. The hydrazo groups were photoconverted mainly into N2 gas (in mineralization yields above 70%) and partially to NH+4 ions (below 10%). The formation of NO+3 ions was scarcely recognized. (C) 2000 Elsevier Science Ltd.
Multiparameter correlation of the rate of a [2 + 2] cycloaddition reaction versus solvophobicity parameter and normalized polarity parameter in aqueous solutions
Gholami,Habibi Yangjeh
, p. 468 - 472 (2000)
The second-order rate constants of the [2 + 2] cycloaddition reaction between diethyl azodicarboxylate and ethyl vinyl ether were obtained spectrophotometrically in various solvents and aqueous solutions of 1,4-dioxane and methanol at 30 ± 0.1 °C. In all media except aqueous solutions, a very good linear correlation of logk2 vs ETN (normalized polarity parameter) was obtained (n = 11, r = 0.991, s = 0.086). Because of the higher polarity of the activated complex relative to the reactants, the rate of the reaction increase with increasing solvent polarity parameter. Dual-parameter correlation of logk2 vs π* (dipolarity/polarizability) and a (hydrogen bonding acidity) also gives good results in various solvents (n = 11, r = 0.985, s = 0.118). Both n* and α have approximately equal effects on the reaction rate. In aqueous solutions of 1,4-dioxane and methanol, the second-order rate constants of the reaction increase dramatically with increasing mole fraction of water. A dual-parameter correlation of logk2 vs Sp (solvophobicity parameter) and ETN was found in aqueous solutions (n = 13, r = 0.988, s = 0.165), in which Sp plays an important role in determining the reaction relative to ETN. This model represents a significant improvement in regression coefficient with respect to the single parameter correlation vs Sp or ETN (r = 0.954 and 0.854, respectively). Similarly to aqueous solutions, a dual-parameter correlation of logk2 vs Sp and ETN was obtained in all media (n = 21, r = 0.987, s = 0.177). Copyright
Green et al.
, p. 3083 (1968)
A convergent synthesis of 1,3,4-oxadiazoles from acyl hydrazides under semiaqueous conditions
Tokumaru, Kazuyuki,Johnston, Jeffrey N.
, p. 3187 - 3191 (2017/04/04)
The 1,3,4-oxadiazole is an aromatic heterocycle valued for its low-lipophilicity in drug development. Substituents at the 2- and/or 5-positions can modulate the heterocycle's electronic and hydrogen bond-accepting capability, while exploiting its use as a carbonyl bioisostere. A new approach to 1,3,4-oxadiazoles is described wherein α-bromo nitroalkanes are coupled to acyl hydrazides to deliver the 2,5-disubstituted oxadiazole directly, avoiding a 1,2-diacyl hydrazide intermediate. Access to new building blocks of oxadiazole-substituted secondary amines is improved by leveraging chiral α-bromo nitroalkane or amino acid hydrazide substrates. The non-dehydrative conditions for oxadiazole synthesis are particularly notable, in contrast to alternatives reliant on highly oxophilic reagents to effect cyclization of unsymmetrical 1,2-diacyl hydrazides. The mild conditions are punctuated by the straightforward removal of co-products by a standard aqueous wash.
Tert-Butyl Iodide Mediated Reductive Fischer Indolization of Conjugated Hydrazones
Ito, Yuta,Ueda, Masafumi,Takeda, Norihiko,Miyata, Okiko
supporting information, p. 2616 - 2619 (2016/02/26)
A novel reductive Fischer indolization of readily available N-aryl conjugated hydrazones with tert-butyl iodide has been developed. In this reaction, tert-butyl iodide is used as anhydrous HI source, and the generated HI acts as a Br?nsted acid and a reducing agent. This operationally simple method allows access to various indole derivatives. Furthermore, the procedure can be applied to the synthesis of biologically active compounds.