41123-22-2

Basic information

• Product Name: 5-hydroxy-2,3-diphenylbenzo[b]furan
• Synonyms: 5-hydroxy-2,3-diphenylbenzo[b]furan
• CAS NO: 41123-22-2
• Molecular Weight: 286.33
• Mol File: 41123-22-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-hydroxy-2,3-diphenylbenzo[b]furan(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-2,3-diphenylbenzo[b]furan(41123-22-2)
• EPA Substance Registry System: 5-hydroxy-2,3-diphenylbenzo[b]furan(41123-22-2)

Safety Data

• Hazardous Substances Data: 41123-22-2(Hazardous Substances Data)

Upstream product

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 123-31-9 hydroquinone 
• 41904-21-6 1-methylsulphinyl-1-methylthio-2-phenylethylene 

Downstream Products

• 1421703-23-2 5-hydroxy-2,3-diphenylbenzofuran-4,7-dicarbaldehyde 
• 917867-68-6 5-hydroxy-2,3-diphenyl-1-benzofuran-4-carbaldehyde 
• 57056-66-3 4-morpholin-4-ylmethyl-2,3-diphenyl-benzofuran-5-ol 

Relevant articles and documents

Two-step, practical, and diversity-oriented synthesis of multisubstituted benzofurans from phenols through Pummerer annulation followed by cross-coupling

Practical and diversity-oriented synthesis of multisubstituted benzofurans has been accomplished from simple phenols through a Pummerer annulation/cross-coupling sequence. Operationally simple and rapid reactions of phenols with ketene dithioacetal monoxides (KDMs) with the aid of trifluoroacetic anhydride provide the corresponding 2-methylsulfanylbenzo[b]furans. The scope of the reaction encompasses phenols and KDMs having a broad range of substituents. The remaining methylsulfanyl group in the annulation products is converted to various aryl groups through cross-coupling reactions that we improved specially to this end. This two-step approach to multisubstituted benzofurans is powerful enough to synthesize highly fluorescent benzofuran derivatives as well as the naturally occurring Eupomatenoid family.