40925-69-7

Basic information

• Product Name: 2-Amino-3-methoxyphenol
• Synonyms: 2-Amino-3-methoxyphenol
• CAS NO: 40925-69-7
• Molecular Formula: C₇H₉NO₂
• Molecular Weight: 139.15
• Mol File: 40925-69-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 265.1±25.0 °C(Predicted)
• Appearance: /
• Density: 1.219±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 9.38±0.10(Predicted)
• CAS DataBase Reference: 2-Amino-3-methoxyphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-3-methoxyphenol(40925-69-7)
• EPA Substance Registry System: 2-Amino-3-methoxyphenol(40925-69-7)

Safety Data

• Hazardous Substances Data: 40925-69-7(Hazardous Substances Data)

Usage

General Description

2-Amino-3-methoxyphenol, also known as 3-Amino-4-methoxyphenol, is a chemical compound with the molecular formula C7H9NO2. It is a derivative of phenol and contains both amino and methoxy functional groups. 2-Amino-3-methoxyphenol is commonly used in hair dyes and cosmetic products as a colorant due to its ability to produce a range of shades from light red to dark brown. It is also commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. However, it is important to handle this chemical with caution as it can cause skin and eye irritation and may be harmful if ingested or inhaled.

Upstream product

• 601-89-8 2-nitroresorcinol 
• 3114-61-2 2-nitroresorcinol monomethyl ether 
• 40925-62-0 4-methoxy-3H-benzoxazol-2-one 
• 91133-91-4 1-Methoxy-2-acetamino-3-acetoxy-benzol 
• 89232-58-6 O-(3-methoxyphenyl)hydroxylamine 

Downstream Products

• 49698-85-3 N-(2-hydroxy-6-methoxyphenyl)acetamide 
• 1013036-97-9 (3-methoxy-2-propionylaminophenyl) propionate 
• 1013037-13-2 N-(2-hydroxy-6-methoxyphenyl) propionamide 
• 30616-79-6 4-methoxy-2-phenyl-1,3-benzoxazole 

Relevant articles and documents

Phosphodiesterase inhibitors. Part 3: Design, synthesis and structure-activity relationships of dual PDE3/4-inhibitory fused bicyclic heteroaromatic-dihydropyridazinones with anti-inflammatory and bronchodilatory activity

(-)-6-(7-Methoxy-2-trifluoromethylpyrazolo[1,5-a]pyridin-4-yl)-5-methyl-4, 5-dihydro-3-(2H)-pyridazinone (KCA-1490) is a dual PDE3/4 inhibitor that exhibits potent combined bronchodilatory and anti-inflammatory activity. A survey of potential bicyclic heteroaromatic replacement subunits for the pyrazolo[1,5-a]pyridine core of KCA-1490 has identified the 4-methoxy-2- (trifluoromethyl)benzo[d]thiazol-7-yl and 8-methoxy-2-(trifluoromethyl)quinolin- 5-yl analogues as dual PDE3/4-inhibitory compounds that potently suppress histamine-induced bronchoconstriction and exhibit anti-inflammatory activity in vivo.

BENZOXAZINE DERIVATIVES AND USES THEREOF

Compounds of formula (I) or pharmaceutically acceptable salts thereof are provided, wherein each of Z, X, R1, R2, R3, R4, y, n, and Ar are as defined, and described in classes and subclasses herein, which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions thereof, are useful for treating a variety of central nervous system disorders such as schizophrenia.