40463-78-3 Usage
Description
4-Amino-2-hydroxybenzyl alcohol, also known as 4-Amino-saligenin, is a phenolic analog derived from Saligenin, a component found in Salix bark extract. It possesses a minor anti-depressant effect and has potential anti-melanomic properties.
Uses
Used in Pharmaceutical Industry:
4-Amino-2-hydroxybenzyl alcohol is used as a pharmaceutical intermediate for the synthesis of various drugs, particularly those with anti-depressant and anti-melanomic effects.
Used in Antidepressant Applications:
4-Amino-2-hydroxybenzyl alcohol is used as an active pharmaceutical ingredient for the development of antidepressant drugs, due to its minor anti-depressant effect.
Used in Anti-melanomic Applications:
4-Amino-2-hydroxybenzyl alcohol is used as a potential anti-melanomic agent, showing promise in the development of treatments for melanoma, a type of skin cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 40463-78-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,4,6 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 40463-78:
(7*4)+(6*0)+(5*4)+(4*6)+(3*3)+(2*7)+(1*8)=103
103 % 10 = 3
So 40463-78-3 is a valid CAS Registry Number.
40463-78-3Relevant articles and documents
Cardiovascular activity of aromatic guanidine compounds.
Hughes et al.
, p. 1077,1080 (2007/10/04)
A series of aromatic guanidines and several 1-phenylbiguanides was prepared and tested for cardiovascular (CV) effects in anesthetized dogs measuring heart rate, blood pressure, carotid artery blood flow, and myocardial force changes. The predominant CV effect at minimally effective dose was vasoconstriction unassociated with cardiac stimulation. The structure-activity relationships of the compounds were discussed comparing their structural similarities to the beta-phenylethylamines. The most potent members of the series were phenylguanidines substituted in the 3 and 4 positions on the aromatic nucleus with hydroxy or chloro groups. Preliminary mechanism studies indicated that the 3,4-dihydroxyphenylguanidines act at least partially by a direct alpha-adrenergic mechanism
