400838-08-6Relevant articles and documents
A facile method for the rapid and selective deprotection of methoxymethyl (MOM) ethers
Han, Jae Hyun,Kwon, Young Eun,Sohn, Jeong-Hun,Ryu, Do Hyun
experimental part, p. 1673 - 1677 (2010/04/04)
We describe a rapid and efficient method for selective deprotection of methoxymethyl (MOM) ethers using ZnBr2 and n-PrSH, which completely removed MOM from diverse MOM ethers of primary, secondary, and tertiary alcohols or phenol derivatives. The deprotection takes less than ten minutes with both high yield and selectivity in the presence of other protecting groups. In addition, the rapid deprotection of MOM ethers of tertiary hydroxyls in high yield with no epimerization allows MOM to be a suitable protecting group for tertiary alcohols.
Alpha-amino,-thio,-oxo substituted ketones as phospholipase inhibitors
-
, (2008/06/13)
Inhibitors of the cytosolic phospholypase A2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula 1wherein X, Z, X1, R1, Rsup
Deprotection of t-butyldimethylsilyl ethers promoted by cerium(IV) triflate
Bartoli, Giuseppe,Cupone, Giovanna,Dalpozzo, Renato,De Nino, Antonio,Maiuolo, Loredana,Procopio, Antonio,Sambri, Letizia,Tagarelli, Antonio
, p. 5945 - 5947 (2007/10/03)
t-Butyldimetylsilyl ethers are mildly cleft by catalytic amounts of cerium(IV) triflate. Dependence from water amount was observed.
