39830-70-1Relevant articles and documents
A photoactivatable microRNA probe for identification of microRNA targets and light-controlled suppression of microRNA target expression
Chen, Lei,Li, Jinbo,Sun, Yu.,Zhang, Yan
supporting information, p. 627 - 630 (2020/01/29)
Here, we report a novel dual-functional microRNA (miRNA) probe, PA-miRNA, for miRNA target identification and light control of miRNA target expression. PA-miRNA is a miRNA mimic with a 3′-biotin tag linked via a photo-cleavable linker. Using PA-miR-34a, i
Photochemical regulation of gene expression using caged siRNAs with single terminal Vitamin E modification
Ji, Yuzhuo,Yang, Jiali,Wu, Li,Yu, Lijia,Tang, Xinjing
supporting information, p. 2152 - 2156 (2016/02/18)
Caged siRNAs with a single photolabile linker and/or vitamin E (vitE) modification at the 5′ terminal were rationally designed and synthesized. These virtually inactive caged siRNAs were successfully used to photoregulate both firefly luciferase and GFP g
Enantioconvergent hydrolysis of styrene epoxides by newly discovered epoxide hydrolases in mung bean
Xu, Wei,Xu, Jian-He,Pan, Jiang,Gu, Qing,Wu, Xin-Yan
, p. 1737 - 1740 (2007/10/03)
Two novel epoxide hydrolases were discovered in mung bean (Phaseolus radiatus L.) for the first time, either of which can catalyze enantioconvergent hydrolysis of styrene epoxides. Their regioselectivity coefficients are more than 90% for the p-nitrostyrene oxide. Furthermore, the crude mung bean powder was also shown to be a cheap and practical biocatalyst, allowing a one-step asymmetric synthesis of chiral (R)-diols from racemic epoxides, in up to >99% ee and 68.7% overall yield (after recrystallization).