395-44-8 Usage
Description
2-(Trifluoromethyl)benzyl bromide, with the CAS number 395-44-8, is a colorless to light yellow liquid that serves as a valuable research chemical. It is characterized by its trifluoromethyl group attached to a benzyl bromide structure, which contributes to its unique chemical properties and potential applications in various fields.
Uses
Used in Research and Development:
2-(Trifluoromethyl)benzyl bromide is used as a research chemical for the development and study of new compounds and materials. Its unique structure allows for the exploration of its properties and potential applications in various scientific and industrial domains.
Used in Chemical Synthesis:
2-(Trifluoromethyl)benzyl bromide is used as a synthetic building block in the chemical industry. Its trifluoromethyl group and benzyl bromide structure make it a versatile starting material for the synthesis of a wide range of compounds, including pharmaceuticals, agrochemicals, and specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(Trifluoromethyl)benzyl bromide is used as a key intermediate in the synthesis of various drugs. Its unique structure can be exploited to create new drug candidates with improved pharmacological properties, such as enhanced potency, selectivity, and bioavailability.
Used in Agrochemical Industry:
2-(Trifluoromethyl)benzyl bromide is also used in the agrochemical industry for the synthesis of novel pesticides and other crop protection agents. Its incorporation into these compounds can lead to improved performance, such as increased efficacy, reduced environmental impact, and better safety profiles.
Used in Specialty Chemicals:
In the specialty chemicals sector, 2-(Trifluoromethyl)benzyl bromide is utilized for the development of advanced materials with specific properties, such as high thermal stability, chemical resistance, or unique optical characteristics. These materials can find applications in various industries, including electronics, coatings, and adhesives.
Check Digit Verification of cas no
The CAS Registry Mumber 395-44-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 5 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 395-44:
(5*3)+(4*9)+(3*5)+(2*4)+(1*4)=78
78 % 10 = 8
So 395-44-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H7F3/c1-2-7-5-3-4-6-8(7)9(10,11)12/h2-6H,1H2
395-44-8Relevant articles and documents
Synthesis of Alkyl Halides from Aldehydes via Deformylative Halogenation
Liang, Shengzong,Kumon, Tatsuya,Angnes, Ricardo A.,Sanchez, Melissa,Xu, Bo,Hammond, Gerald B.
, p. 3848 - 3854 (2019/05/24)
An unprecedented deformylative halogenation of aldehydes to alkyl halides is presented. Under oxidative conditions, 1,4-dihydropyridine (DHP), derived from an aldehyde, generated a C(sp3)- radical that coupled with a halogen radical that was generated from inexpensive and atom-economical halogen sources (NaBr, NaI, or HCl), to yield an alkyl halide. Because of the mild conditions, a wide range of functional groups were tolerated, and excellent site selectivity was achieved.
Sulfonamides and uses
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, (2008/06/13)
Sulfonamides of formula I, in which the symbols R1 -R6, X, Y and n have the significance given in the description and which are in part novel compounds, and salts thereof, which can be used as active ingredients for the manufacture of medicaments for the treatment of circulatory disorders, especially hypertension, ischemia, vasospasms and angina pectoris, are described.