3887-13-6 Usage
Description
GLY-GLY-GLY-GLY-GLY-GLY, also known as hexaglycine, is a peptide composed of six glycine amino acid residues linked together. It is a simple and versatile molecule that serves as a useful model compound in various scientific studies and applications.
Uses
Used in Physicochemical Studies:
GLY-GLY-GLY-GLY-GLY-GLY is used as a model compound in physicochemical studies of peptide structure and dynamics. Its simple structure allows researchers to investigate the fundamental properties of peptides and their interactions with other molecules.
Used in Peptide Quantitation and Separation Methods:
GLY-GLY-GLY-GLY-GLY-GLY is used as a model compound in the development of peptide quantitation and separation methods. Its unique properties make it an ideal candidate for optimizing techniques such as chromatography and mass spectrometry, which are essential tools in proteomics and peptide research.
Used in Pharmaceutical and Biomedical Research:
Hexaglycine and its capped derivatives are used in pharmaceutical and biomedical research to study the properties and behavior of peptides in various biological systems. This knowledge can contribute to the development of new drugs, therapies, and diagnostic tools.
Used in Food and Cosmetic Industries:
Hexaglycine and its derivatives may also find applications in the food and cosmetic industries, where they can be used as stabilizers, emulsifiers, or as components of active ingredients in various products. Their safety and biocompatibility make them attractive candidates for these applications.
Check Digit Verification of cas no
The CAS Registry Mumber 3887-13-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,8 and 7 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 3887-13:
(6*3)+(5*8)+(4*8)+(3*7)+(2*1)+(1*3)=116
116 % 10 = 6
So 3887-13-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H20N6O7/c13-1-7(19)14-2-8(20)15-3-9(21)16-4-10(22)17-5-11(23)18-6-12(24)25/h1-6,13H2,(H,14,19)(H,15,20)(H,16,21)(H,17,22)(H,18,23)(H,24,25)
3887-13-6Relevant articles and documents
Mechanochemical Prebiotic Peptide Bond Formation**
Cindro, Nikola,Grube?i?, Sa?a,Hernández, José G.,Me?trovi?, Ernest,Stolar, Tomislav,U?arevi?, Krunoslav
supporting information, p. 12727 - 12731 (2021/05/07)
The presence of amino acids on the prebiotic Earth, either stemming from endogenous chemical routes or delivered by meteorites, is consensually accepted. Prebiotically plausible pathways to peptides from inactivated amino acids are still unclear as most oligomerization approaches rely on thermodynamically disfavored reactions in solution. Now, a combination of prebiotically plausible minerals and mechanochemical activation enables the oligomerization of glycine at ambient temperature in the absence of water. Raising the reaction temperature increases the degree of oligomerization concomitantly with the formation of a commonly unwanted cyclic glycine dimer (DKP). However, DKP is a productive intermediate in the mechanochemical oligomerization of glycine. The findings of this research show that mechanochemical peptide bond formation is a dynamic process that provides alternative routes towards oligopeptides and establishes new synthetic approaches for prebiotic chemistry.