3796-63-2 Usage
Description
(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one, also known as Teprenone, is an organic compound with a unique structure characterized by four methyl groups and four carbon-carbon double bonds. It is an isomer of Teprenone (T103500) and has been found to have various biological activities, making it a potential candidate for pharmaceutical and industrial applications.
Uses
Used in Pharmaceutical Industry:
Teprenone is used as an anti-ulcerative agent for the treatment of gastric and intestinal lesions. It is particularly effective in protecting against NSAID-induced ulcers by inducing the expression of HSP70, a heat shock protein that plays a role in cellular protection and repair.
Used in Drug Delivery Systems:
In the field of drug delivery, Teprenone can be employed to enhance the efficacy of other therapeutic agents. Its ability to induce the expression of heat shock proteins, such as HSP70, HSPB8, and HSPB1, can potentially improve the delivery and bioavailability of various drugs, leading to better therapeutic outcomes.
Used in Anticancer Applications:
Although not explicitly mentioned in the provided materials, the structural similarity of Teprenone to other bioactive compounds suggests that it may also have potential applications in cancer research and treatment. Further studies are needed to explore its potential as an anticancer agent or in combination with other chemotherapeutic drugs to enhance their efficacy and overcome drug resistance.
Check Digit Verification of cas no
The CAS Registry Mumber 3796-63-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,9 and 6 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 3796-63:
(6*3)+(5*7)+(4*9)+(3*6)+(2*6)+(1*3)=122
122 % 10 = 2
So 3796-63-2 is a valid CAS Registry Number.
InChI:InChI=1/C23H38O/c1-18(2)10-8-12-20(5)14-15-23(17-22(7)24)16-21(6)13-9-11-19(3)4/h10-11,14,16,23H,8-9,12-13,15,17H2,1-7H3/b20-14+,21-16+
3796-63-2Relevant articles and documents
Superacidic low-temperature cyclization of terpenols and their acetates
Vlad, P. F.,Ungur, N. D.,Nguen Van Hung,Perutsky, V. B.
, p. 2391 - 2403 (2007/10/03)
The superacidic low-temperature cyclization of terpenols and their acetates be fluorosulfonic acid represents a highly efficient chemo- and structurally selective and stereospecific process.Homoallylic alcohols (α-isomers of cycloterpenols) are the products of cyclization of terpenols; the configuration of the hydroxymethyl group in the products is predetermined by the configuration of the allylic double bond in aliphatic or partially cyclized precursors.The cyclization of terpenyl acetates yields monoacetates of fully cyclized diastereomeric primary-tertiary γ-diols.Their stereochemistry also depends on the configuration of the allylic double bond in the starting substrates. - Key words: terpenols; terpenyl acetates; cyclization, fluorosulfonic acid, drimanes, isoagathanes, scarlanes.
Structure and Biosynthesis of Cleomeprenols from the Leaves of Cleome spinosa
Suga, Takayuki,Shishibori, Tsuyoshi
, p. 2098 - 2104 (2007/10/02)
Cleomeprenols isolated from Cleome spinosa L. (Capparidaceae) have been identified as nonaprenol (1), decaprenol (2), and undecaprenol (3), which are composed of an ω-terminal isoprene, three internal E-isoprene, and the remaining Z-isoprene residues, respectively.Feeding experiments using stereospecifically double-labelled radioactive mevalonate showed that all the cleomeprenols are composed of four biogenetically E- and the remaining biogenetically Z-isoprene residues.Occurence of the succesive cis-condensation of isoprene residues with (2E,6E,10E)-geranylgeranyl pyrophosphate was demonstrated by comparing the incorporation of a homologue of all-E-prenyl pyrophosphates with that of the corresponding 2Z-isomer.
