37696-01-8 Usage
Description
1-(2-(3-Methoxyphenyl)ethynyl)benzene, also known as 3-Methoxy-1-(2-phenylethynyl)benzene, is an organic compound characterized by its unique chemical structure with the chemical formula C15H12O. It is a phenylacetylene derivative featuring a methoxy group attached to the phenyl ring, which contributes to its distinct properties and potential applications.
Uses
Used in Pharmaceutical Synthesis:
1-(2-(3-METHOXYPHENYL)ETHYNYL)BENZENE is used as a key intermediate for the synthesis of various pharmaceuticals. Its unique chemical structure allows it to serve as a versatile building block in the development of new drugs and therapeutic agents.
Used in Metal Catalysis:
In the field of catalysis, 1-(2-(3-METHOXYPHENYL)ETHYNYL)BENZENE acts as a ligand for metal catalysis. Its interaction with metal catalysts can enhance the efficiency and selectivity of various chemical reactions, making it a valuable component in the synthesis of complex molecules.
Used in Materials Science:
1-(2-(3-METHOXYPHENYL)ETHYNYL)BENZENE has potential applications in the field of materials science. Its unique properties can be exploited to develop new materials with specific characteristics, such as improved mechanical strength, thermal stability, or electrical conductivity.
Used in Organic Chemistry:
As a phenylacetylene derivative, 1-(2-(3-METHOXYPHENYL)ETHYNYL)BENZENE is a valuable precursor for the synthesis of complex organic molecules. Its ethynyl and methoxyphenyl groups can be further modified or functionalized to create a wide range of organic compounds with diverse applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 37696-01-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,6,9 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 37696-01:
(7*3)+(6*7)+(5*6)+(4*9)+(3*6)+(2*0)+(1*1)=148
148 % 10 = 8
So 37696-01-8 is a valid CAS Registry Number.
37696-01-8Relevant articles and documents
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Olofson,R.A.,Dougherty,C.M.
, p. 582 - 584 (1973)
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Synthesis of N-Heterocyclic Carbine Silver(I) and Palladium(II) Complexes with Acylated Piperazine Linker and Catalytic Activity in Three Types of C—C Coupling Reactions
Liu, Qingxiang,Zhang, Xiantao,Zhao, Zhixiang,Li, Xinying,Zhang, Wei
supporting information, p. 605 - 613 (2021/02/01)
Two bis-imidazolium salts LH2·Cl2 and LH2·(PF6)2 with acylated piperazine linker and two N-heterocyclic carbene (NHC) silver(I) and palladium(II) complexes [L2Ag2](PF6)2 (1) and [L2Pd2Cl4] (2) were prepared. The crystal structures of LH2·Cl2 and 1 were confirmed by X-ray analysis. In 1, one 26-membered macrometallocycle was generated through two silver(I) ions and two bidentate ligands L. The catalytic activity of 2 was investigated in Sonogashira, Heck-Mizoroki and Suzuki-Miyaura reactions. The results displayed that these C—C coupling reactions can be smoothly carried out under the catalysis of 2.
Facile one-pot synthesis of diarylacetylenes from arylaldehydes: Via an addition-double elimination process
Chen, Jianyang,Zhang, Xuan,Wu, Jiajun,Wang, Rui,Lei, Chunlin,An, Yanan
, p. 4701 - 4705 (2021/06/11)
A practical one-pot protocol has been developed to synthesize diarylacetylenes from arylaldehydes by treatment with 1-(arylmethyl)benzotriazoles and LiN(SiMe3)2. The reaction proceeded through imine formation, Mannich-type addition and double elimination to deliver products in up to 99% yields with broad substrate scope. In addition, gram-scale synthesis of 1-bromo-4-(phenylethynyl)benzene has been demonstrated.
