35761-54-7

Basic information

• Product Name: (24S)-20,24-Epoxy-25-hydroxy-5α-dammaran-3-one
• Synonyms: (24S)-20,24-Epoxy-25-hydroxy-5α-dammaran-3-one;(24S)-20,24-Epoxy-25-hydroxydammaran-3-one;Cabraleon;Cabraleone;Ocotillone
• CAS NO: 35761-54-7
• Molecular Formula: C30H50O3
• Molecular Weight: 458.72
• Mol File: 35761-54-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (24S)-20,24-Epoxy-25-hydroxy-5α-dammaran-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (24S)-20,24-Epoxy-25-hydroxy-5α-dammaran-3-one(35761-54-7)
• EPA Substance Registry System: (24S)-20,24-Epoxy-25-hydroxy-5α-dammaran-3-one(35761-54-7)

Safety Data

• Hazardous Substances Data: 35761-54-7(Hazardous Substances Data)

Usage

General Description

(24S)-20,24-Epoxy-25-hydroxy-5α-dammaran-3-one is a triterpene sapogenin that is derived from plants and has been shown to possess various bioactivities. It has potential anti-inflammatory, antitumor, and antimicrobial properties. (24S)-20,24-Epoxy-25-hydroxy-5α-dammaran-3-one has also been researched for its ability to inhibit the growth of certain cancer cell lines. Additionally, it has been found to have potential in the treatment of osteoporosis, as it has been shown to stimulate osteoblast differentiation and inhibit osteoclast formation. Overall, (24S)-20,24-Epoxy-25-hydroxy-5α-dammaran-3-one exhibits a wide range of pharmacological activities and has potential for use in various fields, including medicine and agriculture.

Upstream product

• 54878-83-0 3β,25-dihydroxy-(20R,24R)-epoxydammaran-16-one 
• 54911-09-0 (20R,24R)-epoxydammaran-3β,25-diol 
• 5986-39-0 3-epiocotillol 

Downstream Products

• 5244-35-9 Acetic acid (3S,5R,8R,9R,10R,14R,17S)-17-[(2S,5R)-5-(1-hydroxy-1-methyl-ethyl)-2-methyl-tetrahydro-furan-2-yl]-4,4,8,10,14-pentamethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 
• 5986-39-0 ocotillol 
• 19865-87-3 cabralelactone 
• 67253-01-4 20S,24S-epoxydammarane-3α,25-diol 

Relevant articles and documents

Dammarane Triterpenes of Trevoa trinervis: Structure and Absolute Stereochemistry of Trevoagenins A, B, and C

Trevoagenins A, B, and C, extracted from Trevoa trinervis Miers, are shown, by chemical and spectral means, to be isomeric dammarane triterpenes posessing the general 3β,25,30-trihydroxy-(20,24)-epoxydammaran-16-one structure with stereoisomeric side-chains of the ocotillol type.Trevoagenin A (20R,24R)-(1),, whose stereochemistry has been esteblished by chemical methods and confirmed by X-ray analysis, was transformed into (20R,24ξ)-ocotillone (26) and the C-24 stereochemistry was assigned as R.As a consequence, the C-24 stereochemistry for ocotillol-related compounds of the (20R)-series, unestablished so far, has been determined.The stereochemistry of trevoagenin B, (20S,24R)-(13), was established by chemical correlation with trevoagenin A.Moreover, trevoagenin B was transformed into ocotillol (20S,24R)-(21) and its recently questioned C-24 stereochemistry has been reaffirmed.Trevoagenin C, (20S,24S)-(17), is the C-24 isomer of trevoagenin B as shown by degradation of both compounds to the lactone (16).