3545-84-4 Usage
Description
(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl trihydrogen diphosphate is a complex organic compound that features a 1,4,7,8-tetrahydropteridin ring and a trihydrogen diphosphate group. (2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl trihydrogen diphosphate is likely involved in biochemical processes related to pteridine metabolism and folate synthesis due to its pteridinylmethyl structure. Pteridines are crucial for various biological functions, including the production of tetrahydrobiopterin, which acts as a cofactor for enzymes involved in neurotransmitter synthesis and nitric oxide production. The diphosphate group present in the compound plays a significant role in cellular energy metabolism and the synthesis of DNA and RNA.
Uses
Further analysis and research are required to fully understand the specific roles and potential applications of (2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl trihydrogen diphosphate in biological systems. Its involvement in pteridine metabolism and folate synthesis suggests that it may have potential applications in the following areas:
Used in Pharmaceutical Industry:
(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl trihydrogen diphosphate may be used as a therapeutic agent for conditions related to pteridine metabolism and folate synthesis deficiencies. Its role in these processes could make it a potential candidate for the development of drugs targeting such deficiencies.
Used in Research and Development:
In the field of biochemical research, (2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl trihydrogen diphosphate can be used as a research tool to study the mechanisms of pteridine metabolism, folate synthesis, and the role of tetrahydrobiopterin in neurotransmitter synthesis and nitric oxide production.
Used in Diagnostics:
(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl trihydrogen diphosphate may also have potential applications in diagnostic assays to evaluate the status of pteridine metabolism and folate synthesis in patients, which could aid in the identification of related deficiencies or disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 3545-84-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,4 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3545-84:
(6*3)+(5*5)+(4*4)+(3*5)+(2*8)+(1*4)=94
94 % 10 = 4
So 3545-84-4 is a valid CAS Registry Number.
3545-84-4Relevant articles and documents
Comparative genomics guided discovery of two missing archaeal enzyme families involved in the biosynthesis of the pterin moiety of tetrahydromethanopterin and tetrahydrofolate
De Crecy-Lagard, Valerie,Phillips, Gabriela,Grochowski, Laura L.,Yacoubi, Basma El,Jenney, Francis,Adams, Michael W. W.,Murzin, Alexey G.,White, Robert H.
, p. 1807 - 1816 (2012)
C-1 carriers are essential cofactors in all domains of life, and in Archaea, these can be derivatives of tetrahydromethanopterin (H4-MPT) or tetrahydrofolate (H4-folate). Their synthesis requires 6-hydroxymethyl-7,8-dihydropterin dip
Structure-based design and development of functionalized mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from staphylococcus aureus
Dennis, Matthew L.,Chhabra, Sandeep,Wang, Zhong-Chang,Debono, Aaron,Dolezal, Olan,Newman, Janet,Pitcher, Noel P.,Rahmani, Raphael,Cleary, Ben,Barlow, Nicholas,Hattarki, Meghan,Graham, Bim,Peat, Thomas S.,Baell, Jonathan B.,Swarbrick, James D.
, p. 9612 - 9626 (2015/02/02)
6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK), an enzyme from the folate biosynthesis pathway, catalyzes the pyrophosphoryl transfer from ATP to 6-hydroxymethyl-7,8-dihydropterin and is a yet-to-be-drugged antimicrobial target. Building on ou
