354-27-8 Usage
Description
CHLORODIFLUOROACETYL FLUORIDE, with the chemical formula C2ClF3O and trade name EA-1301, is a colorless, volatile, and highly toxic liquid with a pungent odor. It is a synthetic organic compound primarily used as an intermediate in the production of agrochemicals, pharmaceuticals, and other organic compounds. Additionally, it serves as a highly effective fluorinating agent in organic synthesis. Due to its toxicity and potential harmful effects on human health and the environment, it is crucial to handle this compound with extreme care.
Uses
Used in Agrochemical Production:
CHLORODIFLUOROACETYL FLUORIDE is used as an intermediate in the production of agrochemicals for its ability to enhance the properties of these chemicals, improving their effectiveness in pest control and crop protection.
Used in Pharmaceutical Production:
In the pharmaceutical industry, CHLORODIFLUOROACETYL FLUORIDE is utilized as an intermediate to synthesize various pharmaceutical compounds, contributing to the development of new drugs and improving the efficacy of existing medications.
Used as a Fluorinating Agent in Organic Synthesis:
CHLORODIFLUOROACETYL FLUORIDE is employed as a highly effective fluorinating agent in organic synthesis, facilitating the incorporation of fluorine atoms into organic molecules, which can significantly alter their chemical and physical properties, leading to improved performance in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 354-27-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,5 and 4 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 354-27:
(5*3)+(4*5)+(3*4)+(2*2)+(1*7)=58
58 % 10 = 8
So 354-27-8 is a valid CAS Registry Number.
InChI:InChI=1/C2ClF3O/c3-2(5,6)1(4)7
354-27-8Relevant articles and documents
SOME PROPERTIES OF POLYFLUOROACYL- AND POLYFLUOROACETONYL FLUOROSULFATES
Fokin, A. V.,Rapkin, A. I.,Krotovich, I. N.,Tatarinov, A. S.,Studnev, Yu. N.
, p. 1263 - 1267 (1987)
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Method of producing acid fluorides from acid chlorides
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Page column 5, (2008/06/13)
Acid fluorides, for example carboxylic acid fluorides and sulfuryl fluoride are produced by reacting the corresponding acid chlorides with hydrogen fluoride adducts of ammonium fluoride or amine hydrofluorides (which act as a catalyst or as a fluorination agent). Consumed HF adducts may be regenerated with HF.
Defluorination of homologous chlorofluoroethers to chlorofluoroacetates
Quan, Heng-Dao,Tamura, Masanori,Gao, Ren-Xiao,Sekiya, Akira
, p. 131 - 134 (2007/10/03)
The research was focused on the defluorination of chlorofluoroethers to corresponding esters using porous aluminum fluoride (PAF) or MFn/PAF. In the work up process, the product was easily separated from the reagent. Thus, the reaction would be a practical preparation method for polyfluorinated esters. Trifluoromethyl chlorodifluoroacetate was obtained by the reaction of 1,2-dichlorotrifluoroethyltrifluoromethyl ether with fuming sulfuric acid in 49% yield.