34916-10-4 Usage
Description
Cyclohexanecarbonitrile, 4-oxo-, also known as 4-Cyanocyclohexanone, is an organic compound with the molecular formula C7H9NO. It is a key intermediate in the synthesis of various pharmaceuticals and chemicals due to its unique structure and reactivity.
Uses
Used in Pharmaceutical Industry:
Cyclohexanecarbonitrile, 4-oxois used as a key intermediate for the preparation of nicotinamides, which serve as phosphodiesterase 4 (PDE4) D isoenzyme inhibitors. These inhibitors play a crucial role in treating various inflammatory and autoimmune diseases by modulating the immune response and reducing inflammation.
Additionally, Cyclohexanecarbonitrile, 4-oxois used as an anthranilic acid replacement in the synthesis of niacin receptor agonists. These agonists are important for the treatment of various conditions, including hypercholesterolemia, atherosclerosis, and other cardiovascular diseases, as they help regulate lipid metabolism and improve overall cardiovascular health.
Check Digit Verification of cas no
The CAS Registry Mumber 34916-10-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,9,1 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 34916-10:
(7*3)+(6*4)+(5*9)+(4*1)+(3*6)+(2*1)+(1*0)=114
114 % 10 = 4
So 34916-10-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H9NO/c8-5-6-1-3-7(9)4-2-6/h6H,1-4H2
34916-10-4Relevant articles and documents
Direct C(sp3)-H Cyanation Enabled by a Highly Active Decatungstate Photocatalyst
Kim, Kunsoon,Lee, Seulchan,Hong, Soon Hyeok
supporting information, p. 5501 - 5505 (2021/07/26)
A highly efficient, direct C(sp3)-H cyanation was developed under mild photocatalytic conditions. The method enabled the direct cyanation of various C(sp3)-H substrates with excellent functional group tolerance. Notably, complex natural products and bioactive compounds were efficiently cyanated.
Preparation method for 4-cyanocyclohexanone
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Paragraph 0018-0022, (2018/08/28)
The invention provides a preparation method for 4-cyanocyclohexanone. The preparation method mainly overcomes the technical problems that conventional synthesis methods have high cost, great consumption of organic solvents and environmental pollution and
Corresponding amine nitrile and method of manufacturing thereof
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Paragraph 0143-0145; 0149; 0160; 0182; 0193; 0215; 0226, (2017/10/22)
The invention relates to a manufacturing method of nitrile. Compared with the prior art, the manufacturing method has the characteristics of significantly reduced using amount of an ammonia source, low environmental pressure, low energy consumption, low production cost, high purity and yield of a nitrile product and the like, and nitrile with a more complex structure can be obtained. The invention also relates to a method for manufacturing corresponding amine from nitrile.