3463-30-7

Basic information

• Product Name: 1-(4-Nitrophenyl)-1H-pyrazole
• Synonyms: 1-(4-NITROPHENYL)-1H-PYRAZOLE;1-(4-Nitrophenyl)-1H-pyrazole95%;1-(4-NITROPHENYL)-1H-PYRAZOLE 95%;1-(4-Nitrophenyl)pyrazole
• CAS NO: 3463-30-7
• Molecular Formula: C₉H₇N₃O₂
• Molecular Weight: 189.17
• Mol File: 3463-30-7.mol
• Article Data: 57

Chemical Properties

• Melting Point: 168.5-169 °C
• Boiling Point: 331.8 °C at 760 mmHg
• Flash Point: 154.5 °C
• Appearance: /
• Density: 1.33g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -0.78±0.10(Predicted)
• CAS DataBase Reference: 1-(4-Nitrophenyl)-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Nitrophenyl)-1H-pyrazole(3463-30-7)
• EPA Substance Registry System: 1-(4-Nitrophenyl)-1H-pyrazole(3463-30-7)

Safety Data

• Hazardous Substances Data: 3463-30-7(Hazardous Substances Data)

Usage

General Description

1-(4-Nitrophenyl)-1H-pyrazole is a chemical compound that belongs to the class of pyrazole derivatives. It is characterized by the presence of a nitrophenyl group attached to the pyrazole ring. 1-(4-Nitrophenyl)-1H-pyrazole has potential applications in the field of organic synthesis and pharmaceutical research due to its unique structural features and potential biological activities. It can be used as a building block in the synthesis of various organic compounds and may also exhibit interesting pharmacological properties. The nitrophenyl group in 1-(4-Nitrophenyl)-1H-pyrazole can impart specific chemical reactivity and interactions, making it a valuable compound for further research and development in various scientific and industrial applications.

Upstream product

• 288-13-1 NH-pyrazole 
• 100-25-4 para-dinitrobenzene 
• 636-99-7 4-nitrophenylhydrazine hydrochloride 
• 100-01-6 4-nitro-aniline 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 24067-17-2 4-nitrophenylboronic acid 
• 350-46-9 4-Fluoronitrobenzene 
• 59-88-1 phenylhydrazine hydrochloride 
• 586-78-7 para-nitrophenyl bromide 
• 100-00-5 4-chlorobenzonitrile 
• 636-98-6 p-nitrobenzene iodide 
• 288-14-2 ISOXAZOLE 
• 64-17-5 ethanol 
• 7664-93-9 sulfuric acid 

Downstream Products

• 68287-79-6 1-(4-nitrophenyl)-1H-pyrazole-4-carboxylic acid 
• 70375-82-5 methyl 1-(4-nitrophenyl)-1H-pyrazole-4-carboxylate 

Relevant articles and documents

Molecular docking and pharmacological/toxicological assessment of a new compound designed from celecoxib and paracetamol by molecular hybridization

Nonsteroidal anti-inflammatory drugs are commonly used worldwide; however, they have several adverse effects, evidencing the need for the development of new, more effective and safe anti-inflammatory and analgesic drugs. This research aimed to design, syn

Fe-MIL-101 modified by isatin-Schiff-base-Co: a heterogeneous catalyst for C-C, C-O, C-N, and C-P cross coupling reactions

A metal-organic framework functionalized with a cobalt-complex is preparedviapost-synthetic modification of Fe-MIL-101-NH2. Initially, Fe-MIL-101-NH2reacted with isatin to produce Fe-MIL-101-isatin-Schiff-base, which can anchor the cobalt by the addition of cobalt acetate. The resulting MOF-Co catalyst is characterized by employing multiple techniques. This new modified MOF acts as a heterogeneous and recyclable catalyst for efficient Ullmann, Buchwald-Hartwig, Hirao, Hiyama and Mizoroki-Heck cross-coupling reactions of several aryl halides/phenylboronic acid/phenyltosylate with phenols, anilines/heterocyclic amines, triethyl phosphite, triethoxyphenylsilane and alkenes and generates the expected coupling products in good to high yields.

L -(-) -Quebrachitol as a Ligand for Selective Copper(0)-Catalyzed N-Arylation of Nitrogen-Containing Heterocycles

l-(-)-Quebrachitol (QCT) has been found as a ligand of copper powder for selective N-arylation of nitrogen-containing heterocycles with aryl halides. Furthermore, another potential catalytic system (copper powder/QCT/t-BuOK) was successfully adapted to unactivated aryl chlorides.