34612-38-9

Basic information

• Product Name: MALTOTETRAOSE
• Synonyms: O-ALPHA-D-GLUCOPYRANOSYL-[(1-4)-O-ALPHA-D-GLUCOPYRANOSYL]2(1-4)-D-GLUCOPYRANOSE;MALTOTETRAOSE;ALPHA-1,4-TETRAGLUCOSE;AMYLOTETRAOSE;ALPHA-D-GLUCOPYRANOSYL-(1->4)-O-ALPHA-D-GLUCOPYRANOSYL-(1->4)-O-ALPHA-D-GLUCOPYRANOSYL-(1->4)-D-GLUCOSE;O-alpha-D-glucopyranosyl-(1->4)-O-alpha-D-glucopyranosyl-(1->4)-O-alpha-D-glucopyranosyl-(1->4)-D-glucose;MALTOTETRAOSE, DP4, 100MG NEAT;MALTOTETRAOSE 95+%
• CAS NO: 34612-38-9
• Molecular Formula: C₂₄H₄₂O₂₁
• Molecular Weight: 666.58
• EINECS: 252-111-0
• Product Categories: Basic Sugars (Mono & Oligosaccharides);Biochemistry;Sugars;Tetrasaccharides;Carbohydrates;Carbohydrates A to;Carbohydrates M-OBiochemicals and Reagents;Polysaccharide;carbohydrate
• Mol File: 34612-38-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 597.68°C (rough estimate)
• Flash Point: 577.3°C
• Appearance: /
• Density: 1.3922 (rough estimate)
• Refractive Index: 170 ° (C=1, H2O)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: H2O: 50 mg/mL, clear, colorless
• PKA: 12.39±0.20(Predicted)
• CAS DataBase Reference: MALTOTETRAOSE(CAS DataBase Reference)
• NIST Chemistry Reference: MALTOTETRAOSE(34612-38-9)
• EPA Substance Registry System: MALTOTETRAOSE(34612-38-9)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• F: 3-10
• Hazardous Substances Data: 34612-38-9(Hazardous Substances Data)

Usage

Description

Maltotetraose is a tetrasaccharide composed of glucose molecules linked by α-1,4 glycosidic bonds. It is found in B. stearothermophilus and has been identified for its various applications in research, diagnostics, and healthcare.

Uses

1. Research and Diagnostic Purposes:
MALTOTETRAOSE is used as a research and diagnostic tool for studying the properties and interactions of carbohydrates and related biological processes.
2. Nutrients and Healthcare:
MALTOTETRAOSE is used as a nutrient and in the healthcare industry, potentially contributing to the development of therapeutic agents and dietary supplements.
3. Antiviral and Anti-inflammatory Applications:
Used in Pharmaceutical Industry:
MALTOTETRAOSE is used as an antiviral agent for inhibiting AIDS virus infection in vitro. It also serves as an anti-inflammatory agent, reducing the levels of tumor necrosis factor-alpha (TNF), interleukin (IL)-1beta, and chemiluminescence activity.
4. Inhibition of Bacterial Growth:
Used in Microbiology:
MALTOTETRAOSE is used as a growth inhibitor for E. carotovora in a cylinder-agar plate assay, demonstrating its potential application in controlling the growth of specific microorganisms without affecting others.
5. Inhibition of TNF-α-induced ICAM-1 Expression:
Used in Cellular and Molecular Biology:
MALTOTETRAOSE is used to inhibit the TNF-α-induced expression of intercellular adhesion molecule-1 (ICAM-1) in MOVAS-1 mouse smooth muscle cells (VSMCs) transfected with an ICAM-1 luciferase reporter, suggesting its potential role in modulating cellular responses and inflammation.

Upstream product

• 50-99-7 D-glucose 
• 7585-39-9 β‐cyclodextrin 
• 2240-27-9 cellopentaose 
• 528-50-7 cellobiose 
• 33404-34-1 cellotriose 

Downstream Products

• 33404-34-1 cellotriose 
• 50-99-7 D-glucose 
• 528-50-7 cellobiose 

Relevant articles and documents

High Yielding Acid-Catalysed Hydrolysis of Cellulosic Polysaccharides and Native Biomass into Low Molecular Weight Sugars in Mixed Ionic Liquid Systems

Ionic media comprising 1-butyl-3-methylimidazolium chloride and the acidic deep eutectic solvent choline chloride/oxalic acid as co-solvent-catalyst, very efficiently convert various cellulosic substrates, including native cellulosic biomass, into water-soluble carbohydrates. The optimum reaction systems yield a narrow range of low molecular weight carbohydrates directly from cellulose, lignocellulose, or algal saccharides, in high yields and selectivities up to 98 %. Cellulose possesses significant potential as a renewable platform from which to generate large volumes of green replacements to many petrochemical products. Within this goal, the production of low molecular weight saccharides from cellulosic substances is the key to success. Native cellulose and lignocellulosic feedstocks are less accessible for such transformations and depolymerisation of polysaccharides remains a primary challenge to be overcome. In this study, we identify the catalytic activity associated with selected deep eutectic solvents that favours the hydrolysis of polysaccharides and develop reaction conditions to improve the outcomes of desirable low molecular weight sugars. We successfully apply the chemistry to raw bulk, non-pretreated cellulosic substances.

Regioselective glucosylation of inositols catalyzed by Thermoanaerobacter sp. CGTase

Monoglucosylated products of l-chiro-, d-chiro-, muco-, and allo-inositol were synthesized by regioselective α-d-glucosylation with cyclodextrin glucosyl transferase from Thermoanaerobacter sp. after hydrolysis of by products with Aspergillus niger glucoamylase. While the reactions carried out with d-chiro-, muco-, and allo-inositol resulted in the regioselective formation of monoglucosylated products, two products were obtained in the reaction with l-chiro-inositol. Through the structural characterization of the glucosylated inositols here we demonstrated that the selectivity observed in the glucosylation of several inositols by Thermoanaerobacter sp. CGTase, is analogous to the specificity observed for the glucosylation of β-d-glucopyranose and equivalent glucosides.