33026-78-7

Basic information

• Product Name: Phosphoric acid, cyclohexylmethyl diphenyl ester
• CAS NO: 33026-78-7
• Molecular Formula: C19H23O4P
• Molecular Weight: 346.363
• Mol File: 33026-78-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phosphoric acid, cyclohexylmethyl diphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphoric acid, cyclohexylmethyl diphenyl ester(33026-78-7)
• EPA Substance Registry System: Phosphoric acid, cyclohexylmethyl diphenyl ester(33026-78-7)

Safety Data

• Hazardous Substances Data: 33026-78-7(Hazardous Substances Data)

Upstream product

• 26386-88-9 diphenyl phosphoryl azide 
• 100-49-2 cyclohexylmethyl alcohol 
• 2524-64-3 chlorophosphoric acid diphenyl ester 

Downstream Products

• 33026-79-8 cyclohexylmethyl 1-monophosphate 

Relevant articles and documents

Recyclable copper catalyst on chitosan for facile preparation of alkyl/aryl mixed phosphates via deaminated esterification between diphenylphosphoryl azides and aliphatic alcohols

An efficient methodology was established for the preparation of alkyl/aryl mixed phosphates under aerobic conditions promoted by a easily recoverable heterogeneous catalyst. This highly active copper catalyst was obtained by directly mixing of copper precursor with chitosan solution, followed by a simple work-up process. In this catalytic system, different phosphoryl azides and aliphatic alcohols were employed to generate desired products in moderate to excellent yields with good functional group tolerance. This protocol provided a practical application of the chitosan supported heterogeneous copper catalyst towards a novel P–O bond formation.

Copper catalyzed synthesis of aryl/alkyl mixed phosphates from diphenylphosphoryl azides and aliphatic alcohols under mild conditions

An efficient and convenient one-pot protocol is developed to prepare aryl/alkyl mixed phosphates in the presence of copper catalyst under exceptionally mild conditions. A series of versatile, ubiquitous, and inexpensive phosphoryl azides and aliphatic alcohols are combined for the first time ever. Diphenylphosphoryl azide is employed as novel phosphors reagent through an unexpected cleavage of P[sbnd]N bond. The transformation is advantageous with respect to a broad of functional group compatibility and different esterification products are isolated in good to excellent results. This new catalytic system represents a superior platform towards a mild, operationally simple, practical, and scalability alternative to access target molecules. Furthermore, a plausible mechanism is proposed based on insightful mechanistic studies.