3257-05-4Relevant articles and documents
The Wittig Reaction with Glutaric and Succinic Anhydrides
Abell, Andrew D.,Doyle, Ian R.,Massy-Westropp, Ralph A.
, p. 2277 - 2287 (2007/10/02)
Six-membered cyclic anhydrides, including glutaric and some of its alkylated derivatives, have been shown to yield enol-lactones with ethoxycarbonylmethylenetriphenylphosphorane; the (E) isomer is formed preferentially.The reactions of methyl-substituted succinic anhydrides with the same phosphorane give predominantly the (E) enol-lactone in all examples.The influence of alkyl substituents on the rates of the reactions and the product ratios in both the succinic and glutaric anhydride series is discussed.
