32451-88-0

Basic information

• Product Name: Isochlorogenic acid C
• Synonyms: ISOCHLOROGENIC ACID C(SH);(1S,3R,4S,5R)-4-((E)-4-(3,4-Dihydroxyphenyl)-2-oxobut-3-en-1-yl)-3-(((E)-3-(3, 4-dihydroxyphenyl);(1S,3R,4S,5R)-4-((E)-4-(3,4-Dihydroxyphenyl)-2-oxobut-3-en-1-yl)-3-(((E)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)-5-hydroxy-1-methylcyclohexanecarboxylic acid;4,5-Dicaffeoylquinic acid;Isochlorogenic acid C;Isochlorogenic acid C，4,5-Dicaffeoylquinic acid;ISOCHLOROGENIC ACID C(RG);Isochlorogenic acid C, 98%, from Lonicera hypoglauca
• CAS NO: 32451-88-0
• Molecular Formula: C25H24O12
• Molecular Weight: 516.453
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;The group of Chlorogenic acid
• Mol File: 32451-88-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 810.8°C at 760 mmHg
• Flash Point: 274.9°C
• Appearance: /
• Density: 1.64g/cm³
• Vapor Pressure: 8.9E-28mmHg at 25°C
• Refractive Index: 1.719
• CAS DataBase Reference: Isochlorogenic acid C(CAS DataBase Reference)
• NIST Chemistry Reference: Isochlorogenic acid C(32451-88-0)
• EPA Substance Registry System: Isochlorogenic acid C(32451-88-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 32451-88-0(Hazardous Substances Data)

Usage

Description

Isochlorogenic acid C, also known as 4,5-dicaffeoylquinic acid, is a type of chlorogenic acid that is a natural compound found in various plants. It possesses a unique chemical structure with two caffeoyl groups attached to a quinic acid moiety, which gives it specific biological properties.

Uses

Used in Pharmaceutical Industry:
Isochlorogenic acid C is used as a selective inhibitor of human immunodeficiency virus type 1 integrase for its potential role in the development of antiretroviral therapies. Its ability to inhibit the integrase enzyme may help in suppressing the replication of the virus and managing the progression of HIV infection.
Used in Antiviral Applications:
Isochlorogenic acid C is employed as an antiviral agent, particularly against human immunodeficiency virus type 1. It targets the integrase enzyme, which is crucial for the virus's replication process, thereby exhibiting inhibitory effects on viral activity and helping in the management of HIV infection.

InChI:InChI=1/C25H24O12/c26-15-5-1-13(9-17(15)28)3-7-21(31)36-20-12-25(35,24(33)34)11-19(30)23(20)37-22(32)8-4-14-2-6-16(27)18(29)10-14/h1-10,19-20,23,26-30,35H,11-12H2,(H,33,34)/b7-3+,8-4+/t19-,20-,23+,25-/m1/s1