319481-14-6Relevant articles and documents
Synthesis of sugar-modified analogs of bredinin (mizoribine), a clinically useful immunosuppressant, by a novel photochemical imidazole ring-cleavage reaction as the key step
Shuto, Satoshi,Haramuishi, Kimiyo,Fukuoka, Masayoshi,Matsuda, Akira
, p. 3603 - 3609 (2000)
The imidazole nucleoside bredinin (mizoribine) is a clinically useful immunosuppressant. Derivatization of bredinin by the usual nucleoside chemistry is often troublesome due to the unusual zwitterionic structure of the base moiety. We achieve the synthes