31739-56-7

Basic information

• Product Name: 2-(1H-PYRROL-1-YL)BENZALDEHYDE
• Synonyms: 2-(1H-PYRROL-1-YL)BENZALDEHYDE;2-pyrrol-1-ylbenzaldehyde
• CAS NO: 31739-56-7
• Molecular Formula: C₁₁H₉NO
• Molecular Weight: 171.2
• Mol File: 31739-56-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 156 °C
• Boiling Point: 312.8 °C at 760 mmHg
• Flash Point: 143 °C
• Appearance: /
• Density: 1.06 g/cm³
• Vapor Pressure: 0.000516mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -5.65±0.70(Predicted)
• CAS DataBase Reference: 2-(1H-PYRROL-1-YL)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1H-PYRROL-1-YL)BENZALDEHYDE(31739-56-7)
• EPA Substance Registry System: 2-(1H-PYRROL-1-YL)BENZALDEHYDE(31739-56-7)

Safety Data

• Hazardous Substances Data: 31739-56-7(Hazardous Substances Data)

Usage

General Description

2-(1H-pyrrol-1-yl)benzaldehyde, also known as pyrrole-2-carboxaldehyde, is a chemical compound with the formula C11H9NO. It consists of a benzene ring with a 2-pyrrole substituent and an aldehyde functional group. 2-(1H-PYRROL-1-YL)BENZALDEHYDE is commonly used in organic synthesis and pharmaceutical research due to its role as a versatile building block for the construction of various biologically active molecules. It is also employed as a reagent in the preparation of heterocyclic compounds, which have potential applications in drug discovery and manufacturing. Additionally, 2-(1H-pyrrol-1-yl)benzaldehyde has been investigated for its potential antimicrobial and antifungal properties, making it a valuable tool in the development of new drugs and treatments for various infectious diseases.

InChI:InChI=1/C11H9NO/c13-9-10-5-1-2-6-11(10)12-7-3-4-8-12/h1-9H

Upstream product

• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 529-23-7 o-aminobenzaldehyde 
• 61034-86-4 2-(pyrrol-1-yl)-benzyl alcohol 
• 134-20-3 2-carbomethoxyaniline 
• 10333-67-2 methyl 2-(1H-pyrrol-1-yl)benzoate 

Downstream Products

• 1026691-83-7 4-(2-trifluoromethyl-phenylamino)-pyrrolo[1,2-a]quinolin-5-ol 
• 1001053-74-2 1-(2-oxiranylphenyl)pyrrole 
• 1197157-00-8 N₄-(1-(2-(1H-pyrrol-1-yl)benzyl)piperidin-4-yl)-N₂-(3-(dimethylamino)propyl)quinazoline-2,4-diamine 
• 1197157-03-1 N₄-(1-(2-(1H-pyrrol-1-yl)benzyl)piperidin-4-yl)-N₂-(3-(diethylamino)propyl)quinazoline-2,4-diamine 
• 1604835-43-9 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(tert-butylamino)-2-oxoethyl}-N-(4-methoxybenzyl)but-2-ynamide 
• 1604835-44-0 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(cyclohexylamino)-2-oxoethyl}-N-(4-methoxybenzyl)but-2-ynamide 
• 1604835-45-1 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(butylamino)-2-oxoethyl}-N-(4-methoxybenzyl)but-2-ynamide 
• 1604835-49-5 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(p-tolylamino)-2-oxoethyl}-N-(4-methoxybenzyl)but-2-ynamide 
• 1604835-53-1 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(tert-butylamino)-2-oxoethyl}-N-(4-methoxybenzyl)-3-phenylpropiolamide 
• 1604835-55-3 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(tert-butylamino)-2-oxoethyl}-N-(4-methoxybenzyl)propiolamide 
• 1604835-46-2 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(tert-butylamino)-2-oxoethyl}-N-(3,4-dimethoxybenzyl)but-2-ynamide 
• 1604835-47-3 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(cyclohexylamino)-2-oxoethyl}-N-(benzo[d][1,3]dioxol-5-ylmethyl)but-2-ynamide 
• 1604835-48-4 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(tert-butylamino)-2-oxoethyl}-N-(benzo[d][1,3]dioxol-5-ylmethyl)pent-2-ynamide 
• 1604835-56-4 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(tert-butylamino)-2-oxoethyl}-N-benzylpropiolamide 

Relevant articles and documents

NOVEL HETEROARYL COMPOUND, ENANTIOMER, DIASTEREOMER OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND ANTIVIRAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT

The present invention relates to a novel heteroaryl compound, an enantiomer, a diastereomer or a pharmaceutically acceptable salt thereof, and an antiviral composition comprising the same as an active ingredient. The novel compounds represented by formula (I) or formula (II) according to the present invention are remarkably superior in antiviral activity against an influenza virus, and furthermore, have low cytotoxicity and thus low adverse effects on a human body. Therefore, a pharmaceutical composition containing the same as an active ingredient can be effectively used for the prevention or treatment of diseases caused by an influenza virus infection.

Morita-Baylis-Hillman route to 4H-pyrrolo[1,2-a][1]benzazepine derivatives

A simple method for synthesizing substituted 4H-pyrrolo[1,2-a][1]benzazepines using acid-assisted cyclization of the Morita-Baylis-Hillman adducts of 2-(1H-pyrrol-1-yl)benzaldehydes with methyl acrylate or methyl vinyl ketone as a key step has been developed.

Lewis acid catalyzed synthesis of 4-aminopyrrolo[1,2-a]quinolin-5-ol derivatives from 2-(1-pyrrolyl)benzaldehyde and isocyanides

Reaction of 2-(1-pyrrolyl)benzaldehyde with isocyanides in the presence of a catalytic amount of boron trifluoride diethyl etherate was followed by treatment with acetic anhydride in pyridine to give the corresponding O-acetyl derivatives of 4-alkyl(or ar