312959-24-3 Usage
Description
1,2,3,4,5-Pentaphenyl-1'-(di-tert-butylphosphino)ferrocene is a sterically hindered phosphine ligand characterized by its pink solid appearance. It is known for its ability to participate in various chemical reactions due to its unique structure and properties.
Uses
Used in Pharmaceutical Industry:
1,2,3,4,5-Pentaphenyl-1'-(di-tert-butylphosphino)ferrocene is used as a catalyst in the pharmaceutical industry for palladium-catalyzed amination, arylation, and etherification reactions of aryl chlorides. Its steric hindrance allows for selective and efficient synthesis of complex molecules, which are often found in pharmaceutical compounds.
Used in Chemical Synthesis:
In the field of chemical synthesis, 1,2,3,4,5-Pentaphenyl-1'-(di-tert-butylphosphino)ferrocene is used as a ligand for Heck and Suzuki reactions. These reactions are crucial for the formation of carbon-carbon and carbon-heteroatom bonds, which are essential in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and advanced materials.
Used in Material Science:
1,2,3,4,5-Pentaphenyl-1'-(di-tert-butylphosphino)ferrocene can also be utilized in material science for the development of novel materials with specific properties. Its unique structure and reactivity make it a valuable component in the design and synthesis of advanced materials with potential applications in various industries, such as electronics, energy storage, and sensors.
Reaction
Ligand used in the preparation of active Pd catalysts for C-C, C-N and C-O bond formation.
Ligand used in Pd-catalyzed α-arylation of azlactones.
Pd-catalyzed α-arylation of esters, amides and aldehydes.
Check Digit Verification of cas no
The CAS Registry Mumber 312959-24-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,9,5 and 9 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 312959-24:
(8*3)+(7*1)+(6*2)+(5*9)+(4*5)+(3*9)+(2*2)+(1*4)=143
143 % 10 = 3
So 312959-24-3 is a valid CAS Registry Number.
312959-24-3Relevant articles and documents
Synthesis, Structure, and Reductive Elimination Chemistry of Three-Coordinate Arylpalladium Amido Complexes
Yamashita, Makoto,Hartwig, John F.
, p. 5344 - 5345 (2007/10/03)
Four three-coordinate arylpalladium amido complexes with a single hindered phosphine were isolated and structurally characterized. Each possessed a T-shaped geometry. Several of these complexes possessed true three-coordinate structures that lacked any additional coordination by ligand C-H bonds. All of the three-coordinate complexes underwent reductive elimination to form the corresponding triarylamine. A comparison of the rate of reaction of the three-coordinate compounds demonstrated that the rate of elimination from the pentaphenylferrocenyl di-tert-butylphosphine complex were the fastest. A comparison of the rates of reactions between three-coordinate and four-coordinate complexes showed that the rates were much faster from the three-coordinate complexes. Copyright
Unusual in situ ligand modification to generate a catalyst for room temperature aromatic C-O bond formation [8]
Shelby,Kataoka,Mann,Hartwig
, p. 10718 - 10719 (2007/10/03)
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