309712-55-8 Usage
Description
GW791343 HCl, also known as GW 791343 Trihydrochloride, is a P2X7 receptor antagonist that functions as an allosteric inhibitor. It exhibits negative allosteric effects at the human P2X7 receptor and positive allosteric effects at the rat P2X7 receptor. The P2X7 receptor plays a crucial role in the presence of inflammatory cells, which are regulated by extracellular ATP.
Uses
Used in Pharmaceutical Industry:
GW791343 HCl is used as an allosteric inhibitor for modulating the activity of the P2X7 receptor. This modulation can potentially impact the presence and regulation of inflammatory cells, making it a valuable compound for the development of therapeutic strategies targeting inflammatory conditions and related diseases.
Used in Research Applications:
GW791343 HCl is used as a research tool for studying the role and function of the P2X7 receptor in various biological processes. By understanding the receptor's interactions and effects, researchers can gain insights into the development of new drugs and therapies for conditions involving inflammation and immune response.
Used in Drug Development:
GW791343 HCl is used as a lead compound in the development of new drugs targeting the P2X7 receptor. Its allosteric modulation properties make it a promising candidate for the creation of novel therapeutics that can potentially treat a range of inflammatory and immune-related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 309712-55-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,9,7,1 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 309712-55:
(8*3)+(7*0)+(6*9)+(5*7)+(4*1)+(3*2)+(2*5)+(1*5)=138
138 % 10 = 8
So 309712-55-8 is a valid CAS Registry Number.
