3064-05-9

Basic information

• Product Name: (+)-Cycloolivil
• Synonyms: (+)-Cycloolivil;(1S)-1α-(3-Methoxy-4-hydroxyphenyl)-3,7-dihydroxy-6-methoxy-1,2,3,4-tetrahydronaphthalene-2β,3α-bismethanol;(2S)-2,3α-Bis(hydroxymethyl)-4β-(3-methoxy-4-hydroxyphenyl)-7-methoxytetralin-2α,6-diol;[1S,(+)]-1,2,3,4-Tetrahydro-3β,7-dihydroxy-1α-(4-hydroxy-3-methoxyphenyl)-6-methoxy-2β,3-naphthalenedimethanol;Isoolivil;(1S,2S,3S)-1,2,3,4-Tetrahydro-3,7-dihydroxy-1-(4-hydroxy-3-methoxyphenyl)-6-methoxy-2,3-naphthalenedimethanol;(2S,3S,4S)-4-(4-Hydroxy-3-methoxyphenyl)-2,3-bis(hydroxymethyl)-7-methoxy-1,2,3,4-tetrahydro-2,6-naphthalenediol
• CAS NO: 3064-05-9
• Molecular Formula: C₂₀H₂₄O₇
• Molecular Weight: 376.40036
• EINECS: 200-258-5
• Mol File: 3064-05-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 175-176℃ (methanol )
• Appearance: /
• Storage Temp.: ?20°C
• CAS DataBase Reference: (+)-Cycloolivil(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-Cycloolivil(3064-05-9)
• EPA Substance Registry System: (+)-Cycloolivil(3064-05-9)

Safety Data

• Hazard Codes: N
• Statements: 50
• Safety Statements: 61
• Hazardous Substances Data: 3064-05-9(Hazardous Substances Data)

Usage

General Description

(+)-Cycloolivil is a natural product derived from olive oil that exhibits potent antioxidant and anti-inflammatory properties. It is a member of the secoiridoid family and has been shown to have significant free radical scavenging activity, making it a promising compound for therapeutic use. Studies have also demonstrated its ability to inhibit the production of inflammatory mediators, suggesting potential applications for the treatment of various inflammatory conditions. Additionally, it has been found to have neuroprotective effects and may have potential in the prevention and treatment of neurodegenerative diseases. Overall, (+)-Cycloolivil shows great promise as a multifaceted compound with potential therapeutic applications in the fields of antioxidant, anti-inflammatory, and neuroprotective medicine.

Upstream product

• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 

Downstream Products

• 120-80-9 benzene-1,2-diol 
• 16462-68-3 iso-olivil dimethyl ether 

Relevant articles and documents

Total Synthesis and Stereochemical Confirmation of (-)-Olivil, (+)-Cycloolivil, (-)-Alashinols F and G, (+)-Cephafortin A, and Their Congeners: Filling in Biosynthetic Gaps

For the first time, we describe the stereocontrolled total syntheses of olivil, cephafortin A, 4-des-O-methyl-4-O-rhamnosyl cephafortin A, and alashinol F from a common precursor using a combination of chemoenzymatic and biomimetic methods for the systematic introduction of functional groups on three vicinal stereogenic carbon atoms. We revised the previously assigned stereochemistry of (+)-cephafortin A, which was reported as the enantiomer. Natural and unnatural congeners provide insights into the biogenetic interrelations of members of this family.