3033-62-3 Usage
Description
Bis(2-dimethylaminoethyl) ether, also known as Bis((dimethylamino)ethyl) ether, is a colorless or yellow liquid with a boiling point of 188°C. It is soluble in water and easily soluble in alcohol and benzene. Bis(2-dimethylaminoethyl) ether is characterized by high catalytic activity, smooth foaming, large tolerance to tin, and ease of formulation adjustment.
Uses
Used in Polyurethane Foam Production:
Bis(2-dimethylaminoethyl) ether is used as an efficient tertiary amine catalyst for the production of flexible polyurethane foams, particularly for high resilience and RIM products. Its use results in better physical and chemical properties of the products, such as resilience and elongation, compared to other products.
Used in Flexible Foam Products:
Bis(2-dimethylaminoethyl) ether is suitable for the production of almost all foam products, mainly for flexible foam products. Its high catalytic activity and smooth foaming properties make it an ideal choice for creating high-quality foam products.
Used in Manufacturing of Flexible Polyurethane Foams:
Bis(2-dimethylaminoethyl) Ether (Potassium Clavulanate EP Impurity M) is specifically used in the manufacturing of flexible polyurethane foams, contributing to the production of resilient and high-quality foam materials.
Safety Note:
Bis(2-dimethylaminoethyl) ether is toxic by inhalation, skin absorption, ingestion, and eye contact, so proper safety measures should be taken during its handling and use.
Preparation
The main methods for the synthesis of Bis(2-dimethylaminoethyl) ether are:(1) reaction of sodium dimethylaminoethanol and SO3 or chlorosulfonic acid;(2) Reaction of trimethylamine with dichloroethyl ether or dimethylaminoethoxyethyl ether;(3) One-step synthesis of dimethylamine and monoethyleneglycol under solid catalyst.
Reactivity Profile
Bis (2-(dimethylamino)ethyl)ether reacts as a base. Reacts exothermically with acids. May form explosive peroxides upon exposure to the air.
Safety Profile
Poison by skin contact.Moderately toxic by ingestion. Experimental reproductiveeffects. A severe skin and eye irritant.
Check Digit Verification of cas no
The CAS Registry Mumber 3033-62-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,0,3 and 3 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3033-62:
(6*3)+(5*0)+(4*3)+(3*3)+(2*6)+(1*2)=53
53 % 10 = 3
So 3033-62-3 is a valid CAS Registry Number.
3033-62-3Relevant articles and documents
Selective Synthesis of Bisdimethylamine Derivatives from Diols and an Aqueous Solution of Dimethylamine through Iridium-Catalyzed Borrowing Hydrogen Pathway
Fujita, Ken-ichi,Jeong, Jaeyoung
, (2021/12/13)
Bisdimethylamine derivatives are an important class of compounds in the polymer and pharmaceutical industries. However, existing methods for the synthesis of these compounds have several drawbacks such as low selectivity, use of toxic reagents, and generation of waste. In this study, a new system was developed for the selective synthesis of bisdimethylamine derivatives using a diol and dimethylamine as starting materials and an iridium complex bearing an N-heterocyclic carbene ligand as catalyst. The starting materials were easily available, less toxic, inexpensive, and easy to handle. The reaction proceeded efficiently through a borrowing hydrogen pathway under aqueous conditions, without any additional organic solvent, to afford various bisdimethylamine derivatives in good to excellent yields.
Method for homogeneously catalyzing alcohol amination
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Paragraph 0068-0074, (2019/02/21)
The invention relates to a method for homogeneously catalyzing alcohol amination. The method comprises the following steps: mixing diethylene glycol or 1,6-hexanediol, dimethylamine, a ruthenium metalcatalyst and a non-polar solvent and carrying out homogeneous catalysis reaction; separating. According to the method provided by the invention, under the catalysis of a noble metal (rhodium, ruthenium and iridium) metallic catalyst, the diethylene glycol which has a cheap price and is easy to obtain or the 1,6-hexanediol is directly subjected to the amination by utilizing the dimethylamine through a one-step method; bis(2-dialkylaminoethyl)ether or N,N,N,N-tetramethylhexanediamine is prepared in a high-conversion-rate and high-selectivity manner.
Synthesis of bis(2-dimethylaminoethyl) ether
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Paragraph 0013, (2017/11/04)
A bis(2-dimethylaminoethyl) ether product is prepared by chlorinating 2-(2-(dimethylamino)ethoxy)ethanol, which is taken as a raw material, by using thionyl chloride to obtain a corresponding chloride; preparing the chloride and trimethylamine into quaternary ammonium salt; drying the obtained quaternary ammonium salt, then using ethylene diamine to enable one methyl of the quaternary ammonium salt to be transferred onto the ethylene diamine at high temperature, and rectifying.