30085-70-2Relevant articles and documents
Reversal of diastereoselectivity in reactions of the trifluoroacetaldehyde ethyl hemiacetal with enamines and imines: Metal-free, complementary anti-and syn-selective synthesis of 4,4,4-trifluoro-1-aryl-3-hydroxy-2-methyl-1-butanones
Funabiki, Kazumasa,Matsunaga, Kei,Gonda, Hiroshi,Yamamoto, Hitoshi,Arima, Takao,Kubota, Yasuhiro,Matsui, Masaki
, p. 285 - 288 (2011)
A complete reversal of diastereoselectivity was observed for reactions of the trifluoroacetaldehyde ethyl hemiacetal with enamines and imines, derived from propiophenones, that produce 4,4,4-trifluoro-1-aryl-3-hydroxy-2-methyl-1- butanones. This process s
Highly diastereo- and enantioselective copper-catalyzed propargylic alkylation of acyclic ketone enamines for the construction of two vicinal stereocenters
Zhang, De-Yang,Zhu, Fu-Lin,Wang, Ya-Hui,Hu, Xin-Hu,Chen, Song,Hou, Chuan-Jin,Hu, Xiang-Ping
supporting information, p. 14459 - 14462 (2015/02/19)
The first highly diastereo- and enantioselective propargylic alkylation of acyclic ketone enamines to form vicinal tertiary stereocenters has been reported by employing copper catalysis in combination with a bulky and structurally rigid tridentate ketimine P,N,N-ligand.
Reactions of enamines with selectfluor: A straightforward route to difluorinated carbonyl compounds
Peng, Weimin,Shreeve, Jean'ne M.
, p. 5760 - 5763 (2007/10/03)
Reactions of enamines, preformed from β-dicarbonyl and monocarbonyl compounds, with Selectfluor (1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2] octane bis(tetrafluoroborate) under mild conditions (triethylamine (TEA) or molecular sieves) easily led to the corresponding difluorinated carbonyl compounds in high yields.
