299-29-6 Usage
Description
Ferrous gluconate is an iron mineral salt used in iron and multivitamin supplements. It is a yellow-gray or light green-yellow fine powder or granules with a slightly caramel-like smell. It is soluble in water and is used to treat or prevent iron deficiency anemia, which is a lack of red blood cells caused by having too little iron in the body.
Uses
Used in Pharmaceutical Industry:
Ferrous gluconate is used as an iron supplement in vitamin pills for the treatment or prevention of iron deficiency anemia.
Used in Olive Industry:
Ferrous gluconate is used by olive growers to darken the olives to a uniform black color, enhancing their appearance and marketability.
Used in Food Industry:
Ferrous gluconate is used as an iron fortifier in various food products such as corn, soy products, breakfast cereals, beverages, and dietary foods, helping to increase their nutritional value and address iron deficiency in the population.
Used in Cosmetics Industry:
Although not explicitly mentioned in the provided materials, ferrous gluconate can also be used as a coloring agent in the cosmetics industry due to its yellowish-gray to pale greenish-yellow color.
Preparation
Ferrous gluconate is prepared from barium gluconate and iron sulfate.
Biological Functions
Ferrous Gluconate is a form of mineral iron for oral administration, Ferrous Gluconate is absorbed in the stomach and small intestine and combines with apoferritin to form ferritin, which is stored in the liver, spleen, red bone marrow, and intestinal mucosa. Important in transport of oxygen by hemoglobin to the tissues, iron is also found in myoglobin, transferrin, and ferritin, and is as a component of many enzymes such as catalase, peroxidase, and cytochromes. (NCI04)
Flammability and Explosibility
Nonflammable
Safety Profile
Poison by
intraperitoneal and intravenous routes.
Moderately toxic by ingestion. Human
systemic effects by ingestion: hypermothty,
diarrhea, nausea, and vomiting.
Experimental reproductive effects.
Questionable carcinogen with experimental
tumorigenic data. When heated to decomposition it emits acrid smoke and
irritating fumes.
Drug interactions
Potentially hazardous interactions with other drugs
Antibacterials: reduced absorption of 4-quinolones
and tetracyclines.
Dimercaprol: avoid concomitant use.
Mycophenolate: may significantly reduce absorption
of mycophenolate.
Metabolism
Following absorption, the majority of iron is bound to
transferrin and transported to the bone marrow where
it is incorporated into haemoglobin. The remainder is
stored within ferritin or haemosiderin or is incorporated
into myoglobin with smaller amounts occurring in haemcontaining enzymes or in plasma bound to transferrin.
Only very small amounts are excreted as the body
reabsorbs the iron after the haemoglobin has broken
down.
Check Digit Verification of cas no
The CAS Registry Mumber 299-29-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,9 and 9 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 299-29:
(5*2)+(4*9)+(3*9)+(2*2)+(1*9)=86
86 % 10 = 6
So 299-29-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H12O7.Fe.H2O/c7-1-2(8)3(9)4(10)5(11)6(12)13;;/h2-5,7-11H,1H2,(H,12,13);;1H2/q;+2;/p-1/t2-,3-,4+,5-;;/m1../s1
