29194-05-6

Basic information

• Product Name: 2-(dibenzylamino)-1-phenylethanol
• Synonyms: 2-(Dibenzylamino)-1-phenylethanol; benzenemethanol, alpha-[[bis(phenylmethyl)amino]methyl]-
• CAS NO: 29194-05-6
• Molecular Formula: C₂₂H₂₃NO
• Molecular Weight: 317.4241
• Mol File: 29194-05-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 468.7°C at 760 mmHg
• Flash Point: 182.6°C
• Density: 1.124g/cm³
• Vapor Pressure: 1.38E-09mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: 2-(dibenzylamino)-1-phenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(dibenzylamino)-1-phenylethanol(29194-05-6)
• EPA Substance Registry System: 2-(dibenzylamino)-1-phenylethanol(29194-05-6)

Safety Data

• Hazardous Substances Data: 29194-05-6(Hazardous Substances Data)

Usage

General Description

2-(dibenzylamino)-1-phenylethanol is a chemical compound with the formula C27H27NO. It is a pale yellow solid that is used in organic synthesis as a chiral auxiliary to induce asymmetric induction in certain reactions. 2-(dibenzylamino)-1-phenylethanol is a chiral molecule, meaning it has non-superimposable mirror images (enantiomers) that can exhibit different biological activities. Its primary application is in the synthesis of pharmaceuticals, agrochemicals, and fragrances. Additionally, it has been studied for its potential use in the development of new drugs and as a building block for the preparation of diverse organic molecules.

Upstream product

• 96-09-3 styrene oxide 
• 103-49-1 dibenzylamine 
• 100-52-7 benzaldehyde 
• 86269-11-6 (Tributylstannyl)methyl methanesulfonate 
• 24431-24-1 2-(dibenzylamino)-1-phenylethan-1-one 

Downstream Products

• 95291-57-9 N,N-Dibenzyl-β-jod-phenaethylamin 
• 17125-29-0 dibenzyl(2-bromo-2-phenylethyl)amine 
• 95291-35-3 N,N-Dibenzyl-2-chlor-2-phenyl-aethylamin 

Relevant articles and documents

Tb2(WO4)3@N-GQDs-FA as an efficient nanocatalyst for the efficient synthesis of β-aminoalcohols in aqueous solution

In the current study, Tb2(WO4)3@N-(GQDs) modified with folic acid (FA) was synthesized during the chemical reaction of terbium (III) tungstate nanoparticles with nitrogen doped graphene quantum dots (N-GQDs) and introduced

Preparation of enantiopure chiral amino- [D1]methyllithium compounds and determination of their micro- and macroscopic configurational stabilities

Chiral amino-[D1]methyllithiums have been tested with regard to their microscopic and macroscopic configurational stabilities. The N-Boc-N-diethoxyphosphinyl-sub-stituted analogue immediately rearranged, showing complete retention of configuration at up t

Ytterbium Triflate and High Pressure-mediated Ring Opening of Epoxides with Amines

Ring opening of epoxides with amines in THF takes place very readily in the presence of catalytic amounts of ytterbium triflate to give the corresponding β-amino alcohols in good to high yields.With tri- and tetra-substituted epoxides, the use of an excess (2 - 3 equiv.) of the amine is needed.The Yb(OTf)3-catalysed reaction of epoxides with amines in CH2Cl2 is quite complex; the yield of amino alcohols is generally lower and depends upon the addition order of the catalyst, amine and epoxide.The ring opening is accomplished also under high pressures in the absence of Yb(OTf)3.Ring opening with a combination of Yb(OTf)3 in CH2Cl2 and high pressure is more effective than the use, independently, of either Yb(OTf)3 or the high-pressure method.Oxetanes and β-lactones undergo ring opening in the presence of Yb(OTf)3.