287952-08-3

Basic information

• Product Name: N-BOC-4-(4-TRIFLUOROMETHYLPHENOXY)PIPERIDINE
• Synonyms: N-BOC-4-(4-TRIFLUOROMETHYLPHENOXY)PIPERIDINE;4-(4-Trifluoromethyl-phenoxy)-pi;1-Boc-4-(4-TrifluoroMethylphenoxy)piperidine;1,1-dimethylethyl 4-[4-(trifluoromethyl)phenoxy]-1-piperidinecarboxylate;tert-Butyl 4-(4-(trifluoromethyl)phenoxy)piperidine-1-carboxylate
• CAS NO: 287952-08-3
• Molecular Formula: C₁₇H₂₂F₃NO₃
• Molecular Weight: 345.36
• Mol File: 287952-08-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 390.108 °C at 760 mmHg
• Flash Point: 189.731 °C
• Appearance: /
• Density: 1.2 g/cm³
• CAS DataBase Reference: N-BOC-4-(4-TRIFLUOROMETHYLPHENOXY)PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BOC-4-(4-TRIFLUOROMETHYLPHENOXY)PIPERIDINE(287952-08-3)
• EPA Substance Registry System: N-BOC-4-(4-TRIFLUOROMETHYLPHENOXY)PIPERIDINE(287952-08-3)

Safety Data

• Hazardous Substances Data: 287952-08-3(Hazardous Substances Data)

Usage

General Description

N-BOC-4-(4-trifluoromethylphenoxy)piperidine is a chemical compound used in organic synthesis and pharmaceutical research. It is a piperidine derivative with a BOC (tert-butyloxycarbonyl) protecting group attached to the nitrogen atom, and a 4-(4-trifluoromethylphenoxy) substituent attached to the piperidine ring. The compound is known for its potential as a building block in the synthesis of various pharmaceuticals and biologically active molecules. It can also be used as a reagent in organic chemistry for the introduction of piperidine-based motifs into complex molecules. Overall, N-BOC-4-(4-trifluoromethylphenoxy)piperidine is a valuable compound with diverse applications in chemical and pharmaceutical research.

Upstream product

• 402-44-8 4-Fluorobenzotrifluoride 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 5382-16-1 4-HYDROXYPIPERIDINE 
• 24424-99-5 di-tert-butyl dicarbonate 
• 402-45-9 4-hydroxybenzotrifluoride 
• 402-43-7 p-trifluoromethylphenyl bromide 

Downstream Products

• 287952-13-0 tetrahydro-4-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]sulfonyl]-2H-pyran-4-carboxylic acid 
• 287953-08-6 tetrahydro-4-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]-sulfonyl]-2H-thiopyran-4-carboxylic acid 
• 287952-12-9 methyl tetrahydro-4-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]sulfonyl]-2H-pyran-4-carboxylate 
• 287952-42-5 methyl 2-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]-sulfonyl]butanoate 
• 287952-11-8 methyl [[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]sulfonyl]acetate 
• 287952-10-7 1-(methylsulfonyl)-4-[4-(trifluoromethyl)phenoxy]piperidine 
• 28033-37-6 4-[4-(trifluoromethyl)-phenoxy]piperidine 
• 287952-09-4 4-[4-(trifluoromethyl)phenoxy]piperidine hydrogen chloride salt 

Relevant articles and documents

COMPOUNDS AND USES THEREOF

The present invention features compounds useful in the treatment of neurological disorders and primary brain cancer. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders and primary brain cancer.

Sulfamato hydroxamic acid metalloprotease inhibitor

A sulfamato hydroxamic acid compound that, inter alia, inhibits matrix metalloprotease (mmp) activity is disclosed as are a process for preparing the same, intermediate compounds useful in those syntheses, and a treatment process that comprises administering a contemplated sulfamato hydroxamic acid compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.