28575-34-0 Usage
Description
ACETYL-PEPSTATIN is an aspartyl protease inhibitor that serves as an effective inhibitor of HIV-1 proteinase (Ki = 20 nM at pH 4.7) and HIV-2 proteinase (Ki = 5 nM at pH 4.7). It is a potent compound with significant applications in the pharmaceutical industry, particularly in the development of treatments for HIV.
Uses
Used in Pharmaceutical Industry:
ACETYL-PEPSTATIN is used as an HIV-1 protease inhibitor for its ability to inhibit the replication of HIV-1 and HIV-2 viruses. By blocking the activity of the protease enzyme, ACETYL-PEPSTATIN prevents the formation of mature, infectious viral particles, thus helping to control the progression of the disease in patients.
ACETYL-PEPSTATIN is also used as a research tool in the study of aspartyl proteases, which are involved in various biological processes and diseases. Its inhibitory properties make it a valuable compound for understanding the mechanisms of these enzymes and for the development of new therapeutic strategies against related conditions.
Biochem/physiol Actions
Target Ki: 20 nM at pH 4.7 against HIV-1 proteinase
Check Digit Verification of cas no
The CAS Registry Mumber 28575-34-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,5,7 and 5 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 28575-34:
(7*2)+(6*8)+(5*5)+(4*7)+(3*5)+(2*3)+(1*4)=140
140 % 10 = 0
So 28575-34-0 is a valid CAS Registry Number.
InChI:InChI=1/C31H57N5O9/c1-15(2)11-21(35-30(44)28(18(7)8)36-31(45)27(17(5)6)33-20(10)37)23(38)13-25(40)32-19(9)29(43)34-22(12-16(3)4)24(39)14-26(41)42/h15-19,21-24,27-28,38-39H,11-14H2,1-10H3,(H,32,40)(H,33,37)(H,34,43)(H,35,44)(H,36,45)(H,41,42)/t19-,21-,22+,23-,24+,27-,28-/m1/s1