2746-34-1 Usage
Description
H-GAMMA-GLU-VAL-OH is a synthetic peptide with a peptide structure consisting of the amino acids gamma-glutamic acid (GAMMA), valine (VAL), and a hydroxyl group (OH) at the C-terminus. It has potential applications in the fields of medicine and biochemistry due to its unique properties and composition.
Uses
Used in Pharmaceutical Industry:
H-GAMMA-GLU-VAL-OH is used as a pharmaceutical agent for its potential therapeutic effects. The gamma-glutamic acid in the compound is known for its role in the metabolism of the amino acid glutamate and its antioxidant properties, which can contribute to the treatment of various diseases and conditions.
Used in Biochemical Research:
H-GAMMA-GLU-VAL-OH is used as a research tool in biochemistry for studying the properties and functions of amino acids and peptides. Its unique structure and composition make it a valuable molecule for investigating peptide chemistry and its potential applications in various biological processes.
Used in Drug Development:
H-GAMMA-GLU-VAL-OH is used in drug development for its potential as a therapeutic agent. H-GAMMA-GLU-VAL-OH's unique properties, such as its antioxidant properties and its role in amino acid metabolism, make it a promising candidate for the development of new drugs and treatments for various diseases and conditions.
Used in Nutritional Supplements:
H-GAMMA-GLU-VAL-OH is used as a nutritional supplement to support protein synthesis and muscle metabolism. The valine in the compound is an essential amino acid that plays a crucial role in these processes, making it a valuable addition to nutritional supplements for athletes and individuals looking to improve their muscle health and performance.
Check Digit Verification of cas no
The CAS Registry Mumber 2746-34-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,4 and 6 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2746-34:
(6*2)+(5*7)+(4*4)+(3*6)+(2*3)+(1*4)=91
91 % 10 = 1
So 2746-34-1 is a valid CAS Registry Number.
2746-34-1Relevant articles and documents
Enzymatic Synthesis of γ-Glutamylvaline to Improve the Bitter Taste of Valine
Suzuki, Hideyuki,Kato, Kenji,Kumagai, Hidehiko
, p. 577 - 580 (2007/10/03)
The taste of several bitter amino acids is reduced, sourness produced, and preference increased by γ-glutamylization. An enzymatic method for synthesizing γ-Glu-Val involving bacterial γ-glutamyltranspeptidase (GGT) was developed. The optimum reaction conditions for the synthesis of γ-Glu-Val were 20 mM Gln, 300 mM Val, and 0.04 U/ml GGT, pH 10. After 3-hr incubation at 37 °C, 17.6 mM γ-Glu-Val was obtained, with the yield being 88%. γ-Glu-Val was purified on a Dowex 1 × 8 column and then identified by NMR.
Synthesis of γ-Glutamylpeptides by γ-Glutamylcysteine Synthetase from Proteus mirabilis
Nakayama, Reiko,Kumagai, Hedehiko,Maruyama, Takashi,Tochikura, Tatsurokuro,Ueno, Tamio,Fukami, Hiroshi
, p. 2839 - 2846 (2007/10/02)
Syntheses of various γ-glutamylpeptides were examined taking use of the highly purified γ-glutamylcysteine synthetase from Proteus mirabilis.The accumulation of each peptide was measured after long time incubation, and good formation was observed in the synthesis of peptides of following amino acids, L-cysteine, L-α-aminobutyrate, L-serine, L-homoserine, glycine, L-alanine, L-norvaline, L-lysine, L-threonine, taurine and L-valine.Peptide syntheses were confirmed by analyses of the component amino acids, after hydrolysis of the peptides.The structure of the glutamylpeptides, especially the peptide-linkage at the γ-carbonyl residue of L-glutamate, was determined by mass spectrometry of the N-trifluoroacetyl methylester derivatives of the glutamylpeptides.Enzymatic synthesis of γ-glutamyl-L-α-aminobutyrate was also confirmed by PMR spectrometry in the comparison with chemically synthesized compound.
