26692-07-9

Basic information

• Product Name: diethyl (4-decyloxy-3-ethoxyanilino)methylenemalonate
• Synonyms: Diethyl (4-decyloxy-3-ethoxyanilino)methylenemalonate; diethyl ({[4-(decyloxy)-3-ethoxyphenyl]amino}methylidene)propanedioate
• CAS NO: 26692-07-9
• Molecular Formula: C₂₆H₄₁NO₆
• Molecular Weight: 463.6068
• EINECS: 247-903-8
• Mol File: 26692-07-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 522.9°C at 760 mmHg
• Flash Point: 270°C
• Density: 1.058g/cm³
• Vapor Pressure: 4.98E-11mmHg at 25°C
• Refractive Index: 1.512
• CAS DataBase Reference: diethyl (4-decyloxy-3-ethoxyanilino)methylenemalonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl (4-decyloxy-3-ethoxyanilino)methylenemalonate(26692-07-9)
• EPA Substance Registry System: diethyl (4-decyloxy-3-ethoxyanilino)methylenemalonate(26692-07-9)

Safety Data

• Hazardous Substances Data: 26692-07-9(Hazardous Substances Data)

Usage

Description

Diethyl (4-decyloxy-3-ethoxyanilino)methylenemalonate is a chemical compound with the molecular formula C24H35NO5. It is a derivative of malonate and contains a long alkyl chain and an aniline group. diethyl (4-decyloxy-3-ethoxyanilino)methylenemalonate has potential applications in the field of organic chemistry and medicinal chemistry. Its specific properties, such as solubility, reactivity, and biological activity, would need to be determined through further experimentation and testing.

Uses

Used in Organic Chemistry:
Diethyl (4-decyloxy-3-ethoxyanilino)methylenemalonate is used as a chemical intermediate for the synthesis of various organic compounds. Its unique structure, including the long alkyl chain and aniline group, allows it to participate in a range of chemical reactions, making it a valuable building block in organic synthesis.
Used in Medicinal Chemistry:
Diethyl (4-decyloxy-3-ethoxyanilino)methylenemalonate is used as a potential pharmaceutical candidate due to its structural features. The presence of the long alkyl chain and aniline group may contribute to its interaction with biological targets, such as enzymes or receptors, and its potential biological activity. Further research and testing would be required to explore its therapeutic potential and develop it into a drug candidate.
Used in Drug Delivery Systems:
Diethyl (4-decyloxy-3-ethoxyanilino)methylenemalonate could be used in the development of drug delivery systems, where its unique structure may facilitate the encapsulation, solubility, or targeted delivery of therapeutic agents. Its properties may be harnessed to improve the bioavailability, stability, or efficacy of drugs, making it a promising component in the design of advanced drug delivery platforms.
Used in Material Science:
The structural features of diethyl (4-decyloxy-3-ethoxyanilino)methylenemalonate may also find applications in material science, where it could be used to develop new materials with specific properties. Its long alkyl chain and aniline group could contribute to the formation of self-assembling structures, polymers, or other materials with potential uses in various industries, such as coatings, adhesives, or sensors.

Upstream product

• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 94-71-3 2-Ethoxyphenol 
• 55483-70-0 3-ethoxy-4-hydroxyaniline 
• 88331-63-9 2-ethoxy-4-nitroso-phenol 
• 112-29-8 1-bromo dodecane 
• 55483-71-1 3-Ethoxy-4-hydroxy-anilinomethylenmalonsaeurediethylester 
• 55483-78-8 4-(decyloxy)-3-ethoxybenzenamine 
• 1216638-27-5 4-decyloxy-3-ethoxyaniline hydrochloride 

Downstream Products

• 18507-89-6 decoquinate 

Relevant articles and documents

Synthetic method of decoquinate

The invention discloses a synthetic method of decoquinate, and belongs to the technical field of pharmaceutical engineering. The synthetic method takes o-hydroxyphenyl ethyl ether as a raw material to prepare decoquinate via the processes of coupling, reduction, condensation, etherification, cyclization and the like. The process of reduction in the method adopts environment-friendly hydrazine hydrate as a reducer to reduce an azo-compound and introduce an amino group, so that the synthetic method is good in selectivity, and environmentally friendly, and beneficial for reducing environmental pollution problems; BTC is adopted as a cyclization reagent in the process of cyclization, so that the condition is mild, the requirement on equipment is lowered, and the cost is reduced.

Synthesis and anticoccidial activities of Quinoline Carboxylate derivatives with Methyl (E)-2-(3-methoxy)acrylate moiety

A series of novel quinoline carboxylate derivatives with methyl (E)-2-(3-methoxy) acrylate group were designed and synthesized as anticoccidial medicines. The structures were confirmed by 1H NMR, IR and HR-MS spectra. The biological activities were primarily evaluated according to the anticoccidial index method. The results indicated that these compounds (7c, 7d, 7e, 7g) exhibited anticoccidial activities against Eimeria tenella. In particular, the anticoccidial index of 6-decyloxy-7-ethoxy-4-{6-[2-(2-methoxy-1-methoxycarbonyl- vinyl)phenoxy]pyrimidin-4-yloxy}- quinoline-3-carboxylic acid ethyl ester (7e) was 168.7, which indicated that the compound has a good anticoccidial activity.

Efficient and practical synthesis of dissymmetrical ethers of 4-nitrocatechol

An efficient and practical synthesis of dissymmetrical ethers of 4-nitrocatechol from 5-nitrosalicyladehyde and 2-hydroxy-5-nitroacetophenone via Baeyer-Villiger oxidation is described. These dissymmetrical ethers are useful in the synthesis of various coccidiostats and other important pharmaceutical intermediates. Copyright Taylor & Francis Group, LLC.