26628-67-1 Usage
Description
N-Methyl-4,4′-methylenedianiline, also known as 4-(4-aminobenzyl)-N-methylaniline, is a derivative of 4,4′-methylenedianiline. It is synthesized through the methylation of 4,4′-methylenedianiline using formaldehyde and has been characterized using 1H NMR and mass spectrometry. N-METHYL-4,4'-METHYLENEDIANILINE has been identified as one of the urinary metabolites during the in vivo metabolism of 4,4′-[14C]-methylenebis(N,N-dimethyl)benzamine (reduced Michler's ketone, RMK) in Osborne-Mendel rats.
Uses
Used in Chemical Synthesis Industry:
N-Methyl-4,4′-methylenedianiline is used as a chemical intermediate for the synthesis of various organic compounds and polymers. Its unique structure allows it to act as a building block in the creation of complex molecules and materials with specific properties.
Used in Research and Development:
N-METHYL-4,4'-METHYLENEDIANILINE serves as a valuable research tool in the study of metabolic pathways and the development of new drugs and therapies. Its identification as a urinary metabolite in the in vivo metabolism of 4,4′-[14C]-methylenebis(N,N-dimethyl)benzamine (RMK) in Osborne-Mendel rats provides insights into the metabolic processes and potential applications in drug metabolism and pharmacokinetics.
Used in Analytical Chemistry:
N-Methyl-4,4′-methylenedianiline can be employed as a reference compound in analytical chemistry for the development and validation of analytical methods, such as chromatography and mass spectrometry. Its well-characterized structure and properties make it suitable for assessing the performance of these techniques in detecting and quantifying similar compounds.
Used in Material Science:
Due to its specific chemical structure, N-Methyl-4,4′-methylenedianiline may have potential applications in the development of new materials with unique properties, such as conductivity, stability, or reactivity. Researchers in material science can explore its potential uses in creating advanced materials for various industries, including electronics, pharmaceuticals, and environmental applications.
Check Digit Verification of cas no
The CAS Registry Mumber 26628-67-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,6,2 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 26628-67:
(7*2)+(6*6)+(5*6)+(4*2)+(3*8)+(2*6)+(1*7)=131
131 % 10 = 1
So 26628-67-1 is a valid CAS Registry Number.
26628-67-1Relevant articles and documents
SILICA-BASED ZINC CATALYSTS. THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES
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Page/Page column 22-28, (2018/12/13)
The present invention relates to silica-based heterogeneous zinc compounds which are suitable as catalysts in the reaction of amines with dialkyl carbonates to produce carbamates. The catalysts have the formula [SiO2]-CH2-CHR-X-COOZn[Y], wherein [SiO2] represents a silica carrier selected from the group consisting of ordered mesoporous silica and irregular amorphous narrow pore silica, R represents a moiety selected from the group consisting of hydrogen, -CH3, and -CH2CH3, preferably hydrogen, X is an aliphatic chain of 2 to 11 carbon atoms that optionally comprises ether moieties and [Y] represents a mono anion. The invention is also directed towards a method for the preparation of the aforementioned compounds and towards method for the alkoxycarbonylation of amines.
Benzotriazole Mediated Synthesis of Methylenebisanilines
Katritzky, Alan R.,Lan, Xiangfu,Lam, Jamshed N.
, p. 341 - 346 (2007/10/02)
Methylenebisanilines and methylenebis(N,N-dialkylaniline)s are prepared by the reactions of 1-hydroxymethylbenzotriazole with anilines and with N,N-dialkylanilines under acidic conditions.Isolation of the intermediate 4-(benzotriazol-1-ylmethyl)anilines and the N,N-dialkyl analogues and their reactions with anilines allow the efficient preparation of both symmetrical and unsymmetrical members of both product classes.
Alkylidene Transfer from Monochloroalkylmercury(II) Compounds to Aromatic Amines; Selective C-Alkylation
Barluenga, Jose,Campos, Pedro J.,Roy, Miguel A.,Asensio, Gregorio
, p. 1420 - 1426 (2007/10/02)
αα-Diarylalkane derivatives have been synthesized from monochloroalkylmercury(II) compounds in a noncarbenoid alkylidene transfer reaction which takes place selectively on the aromatic ring.A mechanism is suggested for this process.Intermediate products are prepared by alternative routes to ascertain their participation in the course of the reaction.As a consequence, two different aryl groups can be successively incorporated into the alkane molecule.