2626-52-0

Basic information

• Product Name: 3-(DIETHYLAMINO)PROPYL ISOTHIOCYANATE
• Synonyms: DIETHYL-(3-ISOTHIOCYANATO-PROPYL)-AMINE;3-(DIETHYLAMINO)PROPYL ISOTHIOCYANATE;3-(DIETHYLAMINO)PROPYL ISOTHIOCYANATE 99%;N,N-diethyl-N-(3-isothiocyanatopropyl)amine;3-Diethylamino-1-propyl isothiocyanate, 97%;Dimethyl-(3-isothiocyanato-propyl)-amine;N,N-diethyl-3-isothiocyanatopropan-1-aMine;3-(Diethylamino)propyl isothiocyate, 99%
• CAS NO: 2626-52-0
• Molecular Formula: C₈H₁₆N₂S
• Molecular Weight: 172.29
• EINECS: -0
• Product Categories: Organic Building Blocks;Sulfur Compounds;Thiocyanates/Isothiocyanates
• Mol File: 2626-52-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 95 °C
• Flash Point: >230 °F
• Appearance: /
• Density: 0.954 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0313mmHg at 25°C
• Refractive Index: n20/D 1.5000(lit.)
• Storage Temp.: Keep Cold
• PKA: 10.14±0.25(Predicted)
• Sensitive: Moisture Sensitive
• BRN: 1757446
• CAS DataBase Reference: 3-(DIETHYLAMINO)PROPYL ISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(DIETHYLAMINO)PROPYL ISOTHIOCYANATE(2626-52-0)
• EPA Substance Registry System: 3-(DIETHYLAMINO)PROPYL ISOTHIOCYANATE(2626-52-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• RIDADR: 2927
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 2626-52-0(Hazardous Substances Data)

Usage

Description

3-(DIETHYLAMINO)PROPYL ISOTHIOCYANATE, also known as DEAP, is an organic compound with the chemical formula C8H12N2S. It is a colorless to pale yellow liquid with a pungent odor and is used as a reagent in the synthesis of various compounds.

Uses

Used in Pharmaceutical Industry:
3-(DIETHYLAMINO)PROPYL ISOTHIOCYANATE is used as a reagent for the synthesis of GCS-g-DEAP, which is glycol chitosan (GCS) grafted with DEAP groups. 3-(DIETHYLAMINO)PROPYL ISOTHIOCYANATE has potential applications in drug delivery systems, as it can enhance the solubility, stability, and bioavailability of drugs, leading to improved therapeutic outcomes.
Used in Chemical Synthesis:
3-(DIETHYLAMINO)PROPYL ISOTHIOCYANATE is also used as a reagent in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its isothiocyanate functional group allows for a wide range of chemical reactions, making it a versatile building block in organic synthesis.

InChI:InChI=1/C8H16N2S/c1-3-10(4-2)7-5-6-9-8-11/h3-7H2,1-2H3

Upstream product

• 75-15-0 carbon disulfide 
• 104-78-9 diethylaminopropylamine 
• 19022-72-1 N-(2-diethylaminopropyl)-dithiocarbamic acid 

Downstream Products

• 97236-87-8 N-<3-Diethylamino-propyl>-thiobenzamid 
• 106859-54-5 N-[3-(Diethylamino)propyl]-3-[3-(trifluoromethyl) phenoxy]-1-azetidinecarbothioamide, oxalate 
• 1290181-77-9 3-(5-(3-(diethylamino)propylamino)-1,3,4-oxadiazol-2-yl)-6-(2-fluoro-4-methoxyphenyl)-4-methyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile 
• 309246-83-1 GVNDNEEGFFSAR 
• 109341-26-6 cyclohexyl-(3-diethylamino-propyl)-carbodiimide 
• 86503-21-1 5-Benzyl-3-(3-diethylamino-propyl)-2-thioxo-imidazolidin-4-one 
• 106476-26-0 N-cyclohexyl-N'-(3-diethylamino-propyl)-thiourea 

Relevant articles and documents

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Synthesis of new alkylaminoalkyl thiosemicarbazones of 3-acetylindole and their effect on DNA synthesis and cell proliferation

The preparation of a number of thiobemicarbazones of 3-acetylindole is described. These compounds were evaluated in vitro for their effect on proliferation and cell-division delays in cultured human peripheral blood lymphocytes, and their effect on DNA synthesit in T-cell leukemia Molt-4 cells.