26259-79-0 Usage
Description
Gamma-humulene, also known as α-caryophyllene, is a naturally occurring sesquiterpene hydrocarbon found in various plants such as hops, cannabis, and sage. It is characterized by its distinctive earthy, woody aroma and is widely used in aromatherapy and herbal medicine. With potential health benefits including anti-inflammatory, analgesic, and appetite-suppressant properties, gamma-humulene has garnered interest for its potential anti-cancer and antibacterial properties, making it a promising candidate for further research and development in both medical and non-medical applications.
Uses
Used in Aromatherapy:
Gamma-humulene is used as a fragrance component in aromatherapy for its earthy, woody aroma, which can help create a calming and soothing atmosphere.
Used in Herbal Medicine:
In herbal medicine, gamma-humulene is used for its potential health benefits, such as its anti-inflammatory, analgesic, and appetite-suppressant properties, making it a valuable component in various herbal remedies.
Used in Anti-inflammatory Applications:
Gamma-humulene is used as an anti-inflammatory agent to help reduce inflammation and alleviate pain associated with various conditions.
Used in Analgesic Applications:
As an analgesic, gamma-humulene is used to help manage and relieve pain, making it a potential alternative to traditional pain relief medications.
Used in Appetite Suppression:
Gamma-humulene is used as an appetite suppressant to help control food intake and support weight management efforts.
Used in Anticancer Research:
In the field of oncology, gamma-humulene is used as a subject of research for its potential anti-cancer properties, with the aim of developing new therapeutic applications for cancer treatment.
Used in Antibacterial Applications:
Gamma-humulene is used in antibacterial applications to help combat bacterial infections and promote overall health.
Used in Flavor and Fragrance Industry:
In the flavor and fragrance industry, gamma-humulene is used as a natural aroma compound to add depth and complexity to various scent profiles in perfumes, candles, and other fragranced products.
Used in Cosmetics and Personal Care Products:
In cosmetics and personal care products, gamma-humulene is used for its potential skin-soothing and anti-inflammatory properties, making it a valuable ingredient in skincare formulations.
Overall, gamma-humulene is a versatile and potentially beneficial chemical compound with a wide range of applications in various industries, from healthcare to personal care, and continues to be a subject of interest for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 26259-79-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,2,5 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 26259-79:
(7*2)+(6*6)+(5*2)+(4*5)+(3*9)+(2*7)+(1*9)=130
130 % 10 = 0
So 26259-79-0 is a valid CAS Registry Number.
InChI:InChI=1/C15H24/c1-13-7-5-8-14(2)10-12-15(3,4)11-6-9-13/h7,10,12H,2,5-6,8-9,11H2,1,3-4H3/b12-10+,13-7+
26259-79-0Relevant articles and documents
Mechanism-Based Post-Translational Modification and Inactivation in Terpene Synthases
Kersten, Roland D.,Diedrich, Jolene K.,Yates, John R.,Noel, Joseph P.
, p. 2501 - 2511 (2015/12/01)
Terpenes are ubiquitous natural chemicals with diverse biological functions spanning all three domains of life. In specialized metabolism, the active sites of terpene synthases (TPSs) evolve in shape and reactivity to direct the biosynthesis of a myriad of chemotypes for organismal fitness. As most terpene biosynthesis mechanistically involves highly reactive carbocationic intermediates, the protein surfaces catalyzing these cascade reactions possess reactive regions possibly prone to premature carbocation capture and potentially enzyme inactivation. Here, we show using proteomic and X-ray crystallographic analyses that cationic intermediates undergo capture by conserved active site residues leading to inhibitory self-alkylation. Moreover, the level of cation-mediated inactivation increases with mutation of the active site, upon changes in the size and structure of isoprenoid diphosphate substrates, and alongside increases in reaction temperatures. TPSs that individually synthesize multiple products are less prone to self-alkylation then TPSs possessing relatively high product specificity. In total, the results presented suggest that mechanism-based alkylation represents an overlooked mechanistic pressure during the evolution of cation-derived terpene biosynthesis.
