26245-56-7

Basic information

• Product Name: N-chloroisopropylamine
• Synonyms: N-chloroisopropylamine;N-Chloro-2-propanamine
• CAS NO: 26245-56-7
• Molecular Formula: C₃H₈ClN
• Molecular Weight: 93.55532
• EINECS: 247-535-8
• Mol File: 26245-56-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 70.2°C at 760 mmHg
• Appearance: /
• Density: 0.948g/cm³
• Vapor Pressure: 130mmHg at 25°C
• Refractive Index: 1.408
• PKA: -0.11±0.70(Predicted)
• CAS DataBase Reference: N-chloroisopropylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-chloroisopropylamine(26245-56-7)
• EPA Substance Registry System: N-chloroisopropylamine(26245-56-7)

Safety Data

• Hazardous Substances Data: 26245-56-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C3H8ClN/c1-3(2)5-4/h3,5H,1-2H3

Upstream product

• 128-09-6 N-chloro-succinimide 
• 75-31-0 isopropylamine 
• 118-52-5 1,3-dichloro-5,5-dimethylhydantoin 

Downstream Products

• 75-31-0 isopropylamine 
• 70441-63-3 4-fluoro-N-isopropyl-aniline 
• 16495-67-3 4-(isopropylamino)anisole 
• 1448171-39-8 C₁₂H₁₇N₃O₃ 

Relevant articles and documents

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[Cp*RhCl2]2-catalyzed ortho-C-H bond amination of acetophenone o-methyloximes with primary N-chloroalkylamines: Convenient synthesis of N-alkyl-2-acylanilines

Rh(iii)-catalyzed aromatic C-H amination of acetophenone o-methyloximes with primary N-chloroalkylamines was developed, and the arylamine products were obtained in up to 92% yield. The reaction probably involves rate-limiting electrophilic C-H bond cleavage (kH/kD = 2).

Kinetic Study of the Formation of N-Chloramines

We studied the kinetics of the chlorination of amines by sodium hypochlorite in strongly alkaline aqueous solution.A reaction mechanism compatible with experimental results is proposed and discussed.