25782-05-2 Usage
Description
8-CHLOROMETHYL-7-METHOXY-3-METHYL FLAVONE is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its unique chemical structure, which includes a flavone backbone with specific functional groups that enable its use in the development of medications.
Uses
Used in Pharmaceutical Synthesis:
8-CHLOROMETHYL-7-METHOXY-3-METHYL FLAVONE is used as an intermediate in the synthesis of Dimefline Hydrochloride (D448250), a new respiratory stimulant drug. Its role in the synthesis process is essential for the development of this medication, which aims to provide relief for patients with respiratory conditions.
Used in Respiratory Stimulant Applications:
In the pharmaceutical industry, 8-CHLOROMETHYL-7-METHOXY-3-METHYL FLAVONE contributes to the creation of Dimefline, a respiratory stimulant that can help improve breathing in patients with respiratory disorders. The compound's involvement in the synthesis of Dimefline highlights its importance in the development of new treatments for respiratory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 25782-05-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,7,8 and 2 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 25782-05:
(7*2)+(6*5)+(5*7)+(4*8)+(3*2)+(2*0)+(1*5)=122
122 % 10 = 2
So 25782-05-2 is a valid CAS Registry Number.
25782-05-2Relevant articles and documents
Preparation method and application of dimenephrine hydrochloride intermediate 7-methoxy-3-methyl flavone
-
, (2021/04/10)
The invention provides a preparation method of a dimenephrine hydrochloride intermediate 7-methoxy 3-methyl flavone, which comprises the following steps: carrying out cyclization reaction on a compound IIa: 2, 4-dihydroxy propiophenone and a compound IIb: benzoyl chloride under the action of sodium benzoate to obtain a compound III: 7-methoxy-3-methyl flavone; according to the preparation method of the intermediate 7-methoxy-3-methyl flavone, provided by the invention, methylated 2, 4-dihydroxy propiophenone and benzoyl chloride are synthesized by adopting a one-step method, so that the prepared intermediate 7-methoxy-3-methyl flavone is high in purity, few in process impurities, high in yield and simple to operate; the invention further provides application of the 7-methoxy 3-methyl flavone in preparation of the dimenephrine hydrochloride, the yield of the dimenephrine hydrochloride is higher, and the specific preparation operation process is simple.
