25612-59-3

Basic information

• Product Name: tocotrienol, delta
• Synonyms: D-δ-Tocotrienol;(2R)-2β,8-Dimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-3,4-dihydro-2H-1-benzopyran-6-ol;(R)-3,4-Dihydro-2,8-dimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol;2H-1-Benzopyran-6-ol, 3,4-dihydro-2,8-dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-, (R-(E,E))-;D-δ-Tocotrienol,(R-(E,E))-3,4-Dihydro-2,8-dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol;D-delta- Tocotrienol;Deltadelta-tocotrienol;tocotrienol, delta
• CAS NO: 25612-59-3
• Molecular Formula: C₂₇H₄₀O₂
• Molecular Weight: 396.6053
• Mol File: 25612-59-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 517.3°Cat760mmHg
• Flash Point: 212.8°C
• Appearance: /
• Density: 0.968g/cm³
• Vapor Pressure: 2.54E-11mmHg at 25°C
• Refractive Index: 1.523
• Storage Temp.: −20°C
• Solubility: Chloroform (Sparingly), Methanol (Slightly)
• PKA: 10.69±0.40(Predicted)
• Stability: Light Sensitive
• CAS DataBase Reference: tocotrienol, delta(CAS DataBase Reference)
• NIST Chemistry Reference: tocotrienol, delta(25612-59-3)
• EPA Substance Registry System: tocotrienol, delta(25612-59-3)

Safety Data

• WGK Germany: 2
• Hazardous Substances Data: 25612-59-3(Hazardous Substances Data)

Usage

Description

Tocotrienol, delta (δ-Tocotrienol) is a tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2 and 8 and a farnesyl chain at position 2. It is a natural substance with vitamin E activity and possesses antioxidant properties.

Uses

Used in Anticancer Applications:
Tocotrienol, delta is used as an anticancer agent for inhibiting the growth of human breast cancer cells. Its antioxidant properties contribute to its potential role in cancer prevention and treatment.
Used in Antioxidant Applications:
Tocotrienol, delta is used as an antioxidant in various industries, such as the pharmaceutical and dietary supplement industries, to protect cells from oxidative damage and maintain overall health.
Used in Pharmaceutical Industry:
Tocotrienol, delta is used as a pharmaceutical agent for its potential therapeutic benefits, including its antioxidant and anticancer properties, which can be utilized in the development of new drugs and treatments for various health conditions.
Used in Dietary Supplements:
Tocotrienol, delta is used as an ingredient in dietary supplements for its health-promoting properties, such as its antioxidant and potential cancer-fighting capabilities, contributing to overall well-being and health maintenance.

InChI:InChI=1/C27H40O2/c1-20(2)10-7-11-21(3)12-8-13-22(4)14-9-16-27(6)17-15-24-19-25(28)18-23(5)26(24)29-27/h10,12,14,18-19,28H,7-9,11,13,15-17H2,1-6H3/b21-12+,22-14+/t27-/m1/s1

Upstream product

• 951404-44-7 2'-phenylsulfonyl-δ-tocotrienyl benzyl ether 
• 95-48-7 ortho-cresol 
• 98-88-4 benzoyl chloride 
• 71528-84-2 4-hydroxy-3-methylphenyl benzoate 
• 102242-36-4 methylhydroquinone dibenzoate 
• 951404-41-4 2,8-dimethyl-6-benzyloxychroman-2-methanol triflate 
• 951404-35-6 2,8-dimethyl-6-benzyloxychroman-2-methanol 
• 951404-39-0 (S)-2-hydroxymethyl-2,8-dimethylchroman-6-ol 
• 951404-37-8 C₁₆H₂₀O₆ 
• 951404-33-4 2,8-dimethyl-6-hydroxychroman-2-methanol 
• 951404-31-2 methyl 2,8-dimethyl-6-benzoyloxychroman-2-carboxylate 

Downstream Products

• 1253279-73-0 (R)-2,8-dimethyl-2-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)chroman-6-yl benzoylcarbamate 
• 1422421-56-4 (R)-2-(1-benzylpiperidin-4-yl)-6,8-dimethyl-8-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)-1,2,3,8,9,10-hexahydrochromeno[5,6-e][1,3]oxazine 
• 1422421-66-6 5-((R)-6,8-dimethyl-8-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)-9,10-dihydrochromeno[5,6-e][1,3]oxazin-2(1H,3H,8H)-yl)pentan-1-ol 
• 1422421-72-4 (R)-2-(3,4-dimethoxyphenethyl)-6,8-dimethyl-8-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)-1,2,3,8,9,10-hexahydrochromeno[5,6-e][1,3]oxazine 
• 1422421-73-5 (R)-3-(3,4-dimethoxyphenethyl)-5,7-dimethyl-7-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)-2,3,4,7,8,9-hexahydrochromeno[7,6-e][1,3]oxazine 
• 1422421-75-7 4-(2-((R)-6,8-dimethyl-8-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)-9,10-dihydrochromeno[5,6-e][1,3]oxazin-2(1H,3H,8H)-yl)ethyl)phenol 
• 1422421-77-9 (R)-6,8-dimethyl-2-(3-nitrobenzyl)-8-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)-1,2,3,8,9,10-hexahydrochromeno[5,6-e][1,3]oxazine 
• 1208120-97-1 phenyl (R)-2,8-dimethyl-2-((3'E,7'E)-4',8',12'-trimethyltrideca-3',7',11'-trienyl)chroman-6-yl iminodicarbonate 
• 1208120-82-4 (R)-2,8-dimethyl-2-((3'E,7'E)-4',8',12'-trimethyltrideca-3',7',11'-trienyl)chroman-6-yl phenylsulfonylcarbamate 
• 1208120-94-8 (R)-2,8-dimethyl-2-((3'E,7'E)-4',8',12'-trimethyltrideca-3',7',11'-trienyl)chroman-6-yl benzylcarbamate 
• 1208120-88-0 (R)-2,8-dimethyl-2-((3'E,7'E)-4',8',12'-trimethyltrideca-3',7',11'-trienyl)chroman-6-yl 4-chlorophenylsulfonylcarbamate 
• 1208120-91-5 (R)-2,8-dimethyl-2-((3'E,7'E)-4',8',12'-trimethyltrideca-3',7',11'-trienyl)chroman-6-yl phenylcarbamate 
• 1208120-85-7 (R)-2,8-dimethyl-2-((3'E,7'E)-4',8',12'-trimethyltrideca-3',7',11'-trienyl)chroman-6-yl tosylcarbamate 

Relevant articles and documents

SYNTHESIS OF TOCOTRIENOLS FROM O-CRESOL DERIVATIVES

The present invention provides an environmentally benign, facile process for preparation of Tocotrienols from commercially available derivatives of o-Cresol.