253315-11-6

Basic information

• Product Name: 2-(4-(tert-butoxycarbonyl)piperazin-1-yl)pyrimidine-5-carboxylic acid
• Synonyms: 2-(4-(tert-butoxycarbonyl)piperazin-1-yl)pyrimidine-5-carboxylic acid
• CAS NO: 253315-11-6
• Molecular Weight: 308.337
• Mol File: 253315-11-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-(4-(tert-butoxycarbonyl)piperazin-1-yl)pyrimidine-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-(tert-butoxycarbonyl)piperazin-1-yl)pyrimidine-5-carboxylic acid(253315-11-6)
• EPA Substance Registry System: 2-(4-(tert-butoxycarbonyl)piperazin-1-yl)pyrimidine-5-carboxylic acid(253315-11-6)

Safety Data

• Hazardous Substances Data: 253315-11-6(Hazardous Substances Data)

Upstream product

• 374930-88-8 tert-butyl 4-(5-bromopyrimidin-2-yl)piperazine-1-carboxylate 
• 124-38-9 carbon dioxide 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 253315-69-4 ethyl 2-(4-(tert-butoxycarbonyl)piperazin-1-yl)pyrimidine-5-carboxylate 
• 89793-12-4 ethyl 2-chloropyrimidine-5-carboxylate 
• 1057682-17-3 5-(4-(1-(imidazo[1,2-a]pyridin-7-yl)ethyl)piperazin-1-yl)-1,3,4-thiadiazol-2-amine 
• 287714-35-6 2-chloro-pyrimidine-5-carboxylic acid methyl ester 

Downstream Products

• 603965-77-1 ethyl 2-(piperazin-1-yl) pyrimidine-5-carboxylate 

Relevant articles and documents

Protein degradation targeting chimera for degrading androgen receptor

The invention relates to a novel difunctional molecule compound based on VHL ligand induction and application of the difunctional molecule compound in synthesis of the compounds and pharmaceutical compositions thereof. The compound is shown as a formula I. The compound can selectively induce AR protein degradation and can be used for treating cancers such as prostatic cancer and breast cancer.

PYRROLOTRIAZINE DERIVATIVES FOR TREATING KIT- AND PDGFRA-MEDIATED DISEASES

The present disclosure provides compounds of Formula I, pharmaceutical salts thereof, and/or solvates of any of the foregoing which are useful for treating diseases and conditions related to mutant KIT and PDGFRa and present an advantageously non-brain pe

ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES

The invention relates to acid addition salts of piperazine derivatives, as well as solid forms, such as polymorphic forms, thereof, which are useful as pharmaceutical ingredients and in particular as glycosidase inhibitors.