25315-30-4

Basic information

• Product Name: 2-bromoethyl 2-oxo-2-phenylacetate
• Synonyms: 2-bromoethyl 2-oxo-2-phenylacetate
• CAS NO: 25315-30-4
• Molecular Weight: 257.084
• Mol File: 25315-30-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-bromoethyl 2-oxo-2-phenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromoethyl 2-oxo-2-phenylacetate(25315-30-4)
• EPA Substance Registry System: 2-bromoethyl 2-oxo-2-phenylacetate(25315-30-4)

Safety Data

• Hazardous Substances Data: 25315-30-4(Hazardous Substances Data)

Upstream product

• 41463-86-9 4,4,4-trifluoro-3-hydroxy-1-phenylbut-2-en-1-one 
• 540-51-2 2-bromoethanol 
• 120-46-7 1,3-diphenylpropanedione 
• 611-73-4 Benzoylformic acid 

Downstream Products

• 100-52-7 benzaldehyde 
• 17157-48-1 bromoacetaldehyde 

Relevant articles and documents

I 2 /TBHP-Promoted Approach to α-Keto Esters from Trifluoromethyl β-Diketones and Alcohols via C-C Bond Cleavage

A metal-free oxidative coupling reaction of trifluoromethyl β-diketones with alcohols for the synthesis of α-keto esters in good to excellent yields has been developed. Preliminary mechanistic studies suggest that an I 2 /TBHP promoted sequential iodination, C-C bond cleavage, C-O bond formation and oxidation pathway is involved in this reaction.

Cu-catalyzed esterification reaction via aerobic oxygenation and C-C bond cleavage: An approach to α-ketoesters

The Cu-catalyzed novel aerobic oxidative esterification reaction of 1,3-diones for the synthesis of α-ketoesters has been developed. This method combines C-C σ-bond cleavage, dioxygen activation and oxidative C-H bond functionalization, as well as provides a practical, neutral, and mild synthetic approach to α-ketoesters which are important units in many biologically active compounds and useful precursors in a variety of functional group transformations. A plausible radical process is proposed on the basis of mechanistic studies.