252554-78-2

Basic information

• Product Name: FMOC-ALA-SER(YME,MEPRO)-OH
• Synonyms: FMOC-ALA-SER(YME,MEPRO)-OH;(4S)-3-[(2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-1-oxopropyl]-2,2-dimethyl-4-oxazolidinecarboxylic acid;Fmoc-Ala-Ser(ψMe,MePro)-OH;Fmoc-L-Ala-L-Ser[PSI(Me,Me)Pro]-OH;Fmoc-Ala-Ser(psiMe,Mepro)-OH Novabiochem;(9H-Fluoren-9-yl)MethOxy]Carbonyl Ala-SerPsi(Me,Me)Pro-OH
• CAS NO: 252554-78-2
• Molecular Formula: C24H26N2O6
• Molecular Weight: 438.47
• Product Categories: peptide
• Mol File: 252554-78-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 682.4±55.0 °C(Predicted)
• Appearance: /
• Density: 1.292
• Storage Temp.: Store at?0-5°C
• PKA: 3.13±0.40(Predicted)
• CAS DataBase Reference: FMOC-ALA-SER(YME,MEPRO)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-ALA-SER(YME,MEPRO)-OH(252554-78-2)
• EPA Substance Registry System: FMOC-ALA-SER(YME,MEPRO)-OH(252554-78-2)

Safety Data

• WGK Germany: WGK 2 water endangering
• Hazardous Substances Data: 252554-78-2(Hazardous Substances Data)

Usage

Description

Fmoc-Ala-Ser(Psi(Me,Me)pro)-OH is a synthetic peptide linker with an Fmoc-protected amine and a terminal carboxylic acid. The Fmoc group can be deprotected under basic conditions to obtain the free amine, which can be used for further conjugations. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g., EDC or HATU) to form a stable amide bond. It is a white to beige powder in appearance.

Uses

Used in Pharmaceutical Industry:
Fmoc-Ala-Ser(Psi(Me,Me)pro)-OH is used as a synthetic peptide linker for the conjugation of various molecules, such as drugs, targeting ligands, or imaging agents, to peptides or proteins. This allows for the development of targeted drug delivery systems, prodrugs, or bioconjugates with improved properties, such as enhanced solubility, stability, or bioavailability.
Used in Research and Development:
Fmoc-Ala-Ser(Psi(Me,Me)pro)-OH is used as a building block in the synthesis of custom peptides, peptide-based therapeutics, or peptide-based research tools. It can be incorporated into peptide sequences to introduce specific functionalities or to study the effects of specific amino acid sequences on peptide properties or biological activities.
Used in Chemical Synthesis:
Fmoc-Ala-Ser(Psi(Me,Me)pro)-OH is used as an intermediate in the synthesis of complex organic molecules, such as pharmaceuticals, agrochemicals, or other specialty chemicals. Its reactivity and functional groups can be exploited in various synthetic transformations, such as amide bond formation, to construct the desired molecular architectures.