24864-19-5

Basic information

• Product Name: 4-(4-BIPHENYLYL)-2-METHYLTHIAZOLE
• Synonyms: 4-(4-BIPHENYLYL)-2-METHYLTHIAZOLE;LABOTEST-BB LT00440880;4-(4-biphenylyl)-2-methyl-1,3-thiazole;4-(4-BIPHENYLYL)-2-METHYLTHIAZOLE 97%;4-(1,1'-Biphenyl-4-yl)-2-methylthiazole;4-(4-Biphenylyl)-2-methylthiazole,97%;2-Methyl-4-(4-biphenyl)thiazole
• CAS NO: 24864-19-5
• Molecular Formula: C₁₆H₁₃NS
• Molecular Weight: 251.35
• EINECS: 246-505-1
• Mol File: 24864-19-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 113-118 °C
• Boiling Point: 431.3°Cat760mmHg
• Flash Point: 218.3°C
• Appearance: Beige-brown crystalline powder
• Density: 1.1486 (rough estimate)
• Vapor Pressure: 3.05E-07mmHg at 25°C
• Refractive Index: 1.5300 (estimate)
• CAS DataBase Reference: 4-(4-BIPHENYLYL)-2-METHYLTHIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-BIPHENYLYL)-2-METHYLTHIAZOLE(24864-19-5)
• EPA Substance Registry System: 4-(4-BIPHENYLYL)-2-METHYLTHIAZOLE(24864-19-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 24/25-26
• Hazardous Substances Data: 24864-19-5(Hazardous Substances Data)

Usage

Chemical Properties

BEIGE-BROWN CRYSTALLINE POWDER

InChI:InChI=1/C16H13NS/c1-12-17-16(11-18-12)15-9-7-14(8-10-15)13-5-3-2-4-6-13/h2-11H,1H3

Upstream product

• 75408-89-8 4-acetylbiphenyl oxime 
• 108-24-7 acetic anhydride 
• 66047-74-3 4-(4-bromophenyl)-2-methyl-1,3-thiazole 
• 98-80-6 phenylboronic acid 
• 24840-75-3 4-(4-chlorophenyl)-2-methyl-1,3-thiazole 
• 635-84-7 4-(chloroacetyl)biphenyl 
• 62-55-5 thioacetamide 

Relevant articles and documents

Access to Thiazole via Copper-Catalyzed [3+1+1]-Type Condensation Reaction under Redox-Neutral Conditions

A new strategy for thiazoles via copper-catalyzed [3+1+1]-type condensation reaction from oximes, anhydrides and potassiumthiocyanate (KSCN) is developed herein. The transformation has good functional group tolerance and various thiazoles were formed smoothly in good to excellent yields under mild reaction conditions. This process involves copper-catalyzed N-O/C-S bond cleavages, activation of vinyl sp2 C-H bond, and C-S/C-N bond formations which are under redox-neutral conditions as well as operational simplicity.