24699-16-9 Usage
Description
Isomangiferin, a member of the class of xanthones, is a naturally occurring compound characterized by its unique structure featuring hydroxy groups at positions 1, 3, 6, and 7, and a 1,5-anhydro-D-glucitol moiety at position 1. It is abundant in the fibrous root of certain plants and has been identified as a key contributor to α-glucosidase inhibitory activity.
Uses
Used in Pharmaceutical Applications:
Isomangiferin is used as a pharmaceutical agent for its α-glucosidase inhibitory activity, which can be beneficial in the management and treatment of diabetes. By inhibiting α-glucosidase, isomangiferin can help regulate blood sugar levels and potentially reduce the risk of diabetes-related complications.
Used in Traditional Medicine:
Isomangiferin is also utilized in traditional medicine, where it is valued for its potential therapeutic properties. Its presence in various plant sources has led to its use in the treatment of a range of health conditions, including inflammation, infection, and other ailments.
Used in Drug Delivery Systems:
Similar to gallotannin, isomangiferin can be incorporated into drug delivery systems to enhance its bioavailability and therapeutic outcomes. By employing various organic and metallic nanoparticles as carriers, the delivery, efficacy, and overall performance of isomangiferin in treating specific health conditions can be improved.
Check Digit Verification of cas no
The CAS Registry Mumber 24699-16-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,6,9 and 9 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 24699-16:
(7*2)+(6*4)+(5*6)+(4*9)+(3*9)+(2*1)+(1*6)=139
139 % 10 = 9
So 24699-16-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H18O11/c20-4-11-15(26)16(27)17(28)19(30-11)13-9(24)2-8(23)12-14(25)5-1-6(21)7(22)3-10(5)29-18(12)13/h1-3,11,15-17,19-24,26-28H,4H2/t11-,15-,16+,17-,19+/m1/s1
24699-16-9Relevant articles and documents
Tannins and Related Compounds. XXI. Isolation and Characterization of Galloyl and p-Hydroxybenzoyl Esters of Benzophenone and Xanthone C-glucosides from Mangifera indica L.
Tanaka, Takashi,Sueyasu, Tokiko,Nonaka, Gen-ichiro,Nishioka, Itsuo
, p. 2676 - 2686 (2007/10/02)
Six new galloyl and p-hydroxybenzoyl esters (2-7) of benzophenone C-glucosides have been isolated, together with a new benzophenone C-glucoside (1), from the leaves of Mangifera indica L. (Anacardiaceae).On the basis of chemical and spectroscopic evidence, the structures of these compounds have been established as maclurin 3-C-β-D-glucoside (1), maclurin 3-C-(6''-O-p-hydroxybenzoyl)-β-D-glucoside (2), maclurin 3-C-(2''-O-galloyl-6''-O-p-hydroxybenzoyl)-β-D-glucoside (3), maclurin 3-C-(2''-O-p-hydroxybenzoyl-6''-O-galloyl)-β-D-glucoside (4), maclurin 3-C-(2'',3'',6''-tri-O-galloyl)-β-D-glucoside (5), iriflophenone 3-C(2'',6''-di-O-galloyl)-β-D-glucoside (6) and iriflophenone 3-C-(2'',3'',6''-tri-O-galloyl)-β-D-glucoside (7). (-)-Epicatechin 3-O-gallate (9), mangiferin (10), isomangiferin (11) and a new xanthone C-glucoside gallate, mangiferin 6'-O-gallate (8), have also been isolated and their structures have been similarly characterized.Furthermore, the above plant source contained polygalloylglucoses which were characterized on the basis of chemical and high performance liquid chromatographic analyses as a mixture of penta- to undecagalloylglucoses based on a 1,2,3,4,6-penta-O-galloyl-β-D-glucose core.Maclurin 3-C-glucoside (1) has been transformed enzymatically to mangiferin (10) and isomangiferin (11), and it has become clear that 1 is a key intermediate in the biosynthesis of 10 and 11. Keywords - Mangifera indica; Anacardiaceae; galloyl maclurin 3-C-glucoside p-hydroxybenzoate; galloyl iriflopenone 3-C-glucoside; galloyl mangiferin; benzophenone C-glucoside; biosynthesys; mangiferin; isomangiferin; galloylglucose
