246876-92-6

Basic information

• Product Name: (S)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE
• Synonyms: H-b-HoPhe(2-F)-OH·HCl;(S)-3-Amino-4-(2-fluoro-phenyl)-butyricacidCl;(S)-3-Amino-4-(2-fluorophenyl)butyric acid hydrochloride;H-β-HoPhe(2-F)-OH.HCl;2-Fluoro-L-β-hoMophenylalanine hydrochloride;(S)-b-Amino-2-fluorobenzenebutanoic acid;L-BETA-HOMO(2-FLUOROPHENYL)ALANINE HYDROCHLORIDE;H-BETA-HOPHE(2-F)-OH HCL
• CAS NO: 246876-92-6
• Molecular Formula: C10H13ClFNO2
• Molecular Weight: 233.67
• Product Categories: B-Amino;3-Amino-4-phenylbutyric Acid Analogs;3-Amino-4-phenylbutanoic Acid Analogs
• Mol File: 246876-92-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 330.2oC at 760 mmHg
• Flash Point: 153.5oC
• Appearance: /
• Density: 1.246±0.06 g/cm3(Predicted)
• Vapor Pressure: 6.77E-05mmHg at 25°C
• PKA: 3.73±0.10(Predicted)
• CAS DataBase Reference: (S)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE(246876-92-6)
• EPA Substance Registry System: (S)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE(246876-92-6)

Safety Data

• Hazardous Substances Data: 246876-92-6(Hazardous Substances Data)

Usage

General Description

(S)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE, also known as baclofen, is a medication that is primarily used to treat muscle spasticity. It is a derivative of gamma-aminobutyric acid (GABA), a neurotransmitter in the central nervous system that inhibits nerve activity. Baclofen works by acting on GABA receptors, which helps to reduce the excessive firing of nerves that can lead to muscle stiffness and spasms. The hydrochloride form of baclofen is the salt form of the drug, which is more stable and water-soluble than the base compound, making it more suitable for pharmaceutical use. It is typically administered orally or intrathecally and has been found to be effective in reducing muscle spasticity associated with conditions such as multiple sclerosis, cerebral palsy, and spinal cord injury. However, it may also cause side effects such as drowsiness, dizziness, and weakness, and should be used with caution in individuals with certain medical conditions.

InChI:InChI=1/C10H12FNO2.ClH/c11-9-4-2-1-3-7(9)5-8(12)6-10(13)14;/h1-4,8H,5-6,12H2,(H,13,14);1H/t8-;/m0./s1