24654-55-5

Basic information

• Product Name: 4-Fluorocinnamaldehyde
• Synonyms: CHEMBRDG-BB 4004292;4-FLUOROCINNAMALDEHYDE;2-PROPENAL, 3-(4-FLUOROPHENYL)-,(2E);4-FLUOROCINNAMALDEHYDE 98+%;p-Fluorocinnamaldehyde;(E)-3-(4-fluorophenyl)acrylaldehyde;4-Fluorociamaldehyde;3-(4-Fluorophenyl)acrylaldehyde 3-(4-Fluorophenyl)-2-propenal
• CAS NO: 24654-55-5
• Molecular Formula: C₉H₇FO
• Molecular Weight: 150.15
• Product Categories: Aromatic Aldehydes & Derivatives (substituted)
• Mol File: 24654-55-5.mol
• Article Data: 60

Chemical Properties

• Melting Point: 24°C
• Boiling Point: 102-104°C
• Flash Point: 91.3 °C
• Appearance: Light yellow crystalline
• Density: 1.18
• Vapor Pressure: 0.0284mmHg at 25°C
• Refractive Index: 1.5960-1.6010
• Storage Temp.: 0-10°C
• CAS DataBase Reference: 4-Fluorocinnamaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Fluorocinnamaldehyde(24654-55-5)
• EPA Substance Registry System: 4-Fluorocinnamaldehyde(24654-55-5)

Safety Data

• Hazardous Substances Data: 24654-55-5(Hazardous Substances Data)

Usage

General Description

4-Fluorocinnamaldehyde is a chemical compound that belongs to the class of cinnamaldehydes, which are organic compounds containing a cinnamaldehyde moiety. It is a pale yellow liquid with a strong odor, and it is commonly used in the synthesis of various pharmaceuticals and organic compounds. 4-Fluorocinnamaldehyde has an aldehyde functional group, a double bond in its carbon chain, and a fluorine atom attached to the fourth carbon of the benzene ring. It is also used in the manufacture of fragrances and flavors due to its pleasant aromatic properties. Additionally, it has been studied for its potential biological activities, including its antimicrobial and antioxidant properties.

InChI:InChI=1/C9H7FO/c10-9-5-3-8(4-6-9)2-1-7-11/h1-7H/b2-1-

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 2136-75-6 (triphenylphosphoranylidene)acetaldehyde 
• 75-07-0 acetaldehyde 
• 3054-95-3 acrylaldehyde diethyl acetal 
• 352-34-1 4-fluoro-1-iodobenzene 
• 405-99-2 para-fluorostyrene 
• 123-73-9 crotonaldehyde 
• 124980-95-6 (E)-3-(4-fluorophenyl)-2-propen-1-ol 
• 819066-29-0 1-((E)-3,3-Diethoxy-propenyl)-4-fluoro-benzene 
• 766-98-3 1-ethynyl-4-fluorobenzene 
• 201230-82-2 carbon monoxide 
• 459-32-5 4-fluorocinnamic acid 
• 100891-10-9 methyl p-fluorocinnamate 
• 124980-95-6 3-(4-fluorophenyl)prop-2-en-1-ol 

Downstream Products

• 819066-29-0 1-((E)-3,3-Diethoxy-propenyl)-4-fluoro-benzene 
• 27331-26-6 1-Fluoro-4-((1E,3Z)-4-phenyl-buta-1,3-dienyl)-benzene 
• 857722-07-7 1-fluoro-4-((1E,3E)-4-phenylbuta-1,3-dien-1-yl)benzene 
• 863970-22-3 (S)-3-(4-fluorophenyl)-3-phenylpropanal 
• 1005470-43-8 2-(4-fluoro-phenyl)-3-formyl-cyclopent-3-ene-1,1-dicarboxylic acid dimethyl ester 
• 1015486-70-0 3-(4-fluoro-phenyl)-oxirane-2-carbaldehyde 
• 1160851-06-8 (2S,3R)-3-(4-fluorophenyl)oxirane-2-carbaldehyde 
• 1020270-25-0 (S)-3-(4-fluorophenyl)-4-nitrobutanal 

Relevant articles and documents

An efficient Pd@Pro-GO heterogeneous catalyst for the α, β-dehydrogenation of saturated aldehyde and ketones

An Efficient Pd@Pro-GO heterogeneous catalyst was developed that can promote the α, β-dehydrogenation of saturated aldehyde and ketones in the yield of 73% ? 92% at mild conditions without extra oxidants and additives. Pd@Pro-GO heterogeneous catalyst was synthesized via two steps: firstly, the Pro-GO was obtained by the esterification reaction between graphene oxide (GO) and N-(tert-Butoxycarbonyl)-L-proline (Boc-Pro-OH), followed by removing the protection group tert-Butoxycarbonyl (Boc), which endowed the proline-functionalized GO with both the lewis acid site (COOH) and the bronsted base site (NH), besides, the pyrrolidine of proline also can form imine with aldehydes to activate these substrates; Second, palladium was dispersed on the proline-functionalized GO (Pro-GO) to obtained heterogeneous catalyst Pd@Pro-GO. Mechanistic studies have shown that the Pd@Pro-GO-catalyzed α,β-dehydrogenation of saturated aldehyde and ketones was realized by an improved heterogeneously catalyzed Saegusa oxidation reaction. Based on the obove characteristics, the Pd@Pro-GO will be widely used in the transition metal catalytic field.

TREATMENT OF DISORDERS ASSOCIATED WITH OXIDATIVE STRESS AND COMPOUNDS FOR SAME

The present invention relates to the treatment of disorders associated with oxidative stress including neuropathic pain and small synthetically derived compounds for treating such disorders.

Selective Rhodium-Catalyzed Hydroformylation of Terminal Arylalkynes and Conjugated Enynes to (Poly)enals Enabled by a π-Acceptor Biphosphoramidite Ligand

The hydroformylation of terminal arylalkynes and enynes offers a straightforward synthetic route to the valuable (poly)enals. However, the hydroformylation of terminal alkynes has remained a long-standing challenge. Herein, an efficient and selective Rh-catalyzed hydroformylation of terminal arylalkynes and conjugated enynes has been achieved by using a new stable biphosphoramidite ligand with strong π-acceptor capacity, which affords various important E-(poly)enals in good yields with excellent chemo- and regioselectivity at low temperatures and low syngas pressures.