2394-68-5 Usage
Description
Ubiquinone 8, also known as Coenzyme Q8 (CoQ8), is a naturally occurring compound found in living organisms. It is a vital component of the electron transfer system and consists of a benzoquinone moiety and an isoprenoid side chain. Ubiquinone 8 is a specific type of ubiquinone with a structure that includes a 2,3-dimethoxy-5-methylbenzoquinone nucleus and a side chain of eight isoprenoid units.
Uses
1. Used in Pharmaceutical Industry:
Ubiquinone 8 is used as a ligand for activating peroxisome proliferator-activated receptor (PPAR), which plays a crucial role in various cellular processes, including lipid metabolism and cell differentiation.
2. Used in Immune System Enhancement:
Ubiquinone 8 serves as an isoprenoid quinone that enhances nonspecific resistance to bacterial infections. It stimulates phagocytosis in macrophages by modulating the kinetics of the Fc receptor, thereby improving the immune system's response to infections.
3. Used in Cellular Respiration:
Ubiquinone 8 acts as an electron carrier from the flavoprotein to the cytochrome complex in reconstituted proteoliposomes. In these systems, cytochrome O complex functions as an efficient ubiquinol-8 oxidase, facilitating the process of cellular respiration and energy production.
Check Digit Verification of cas no
The CAS Registry Mumber 2394-68-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,9 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2394-68:
(6*2)+(5*3)+(4*9)+(3*4)+(2*6)+(1*8)=95
95 % 10 = 5
So 2394-68-5 is a valid CAS Registry Number.
2394-68-5Relevant articles and documents
A convergent approach to coenzyme Q
Lipshutz, Bruce H.,Bulow, Gerd,Fernandez-Lazaro, Fernando,Kim, Sung-Kyu,Lowe, Richard,Mollard, Paul,Stevens, Kirk L.
, p. 11664 - 11673 (2007/10/03)
Syntheses of coenzyme Q3-8 are described, as well as related systems such as plastoquinone-5. Preparation of the higher homologues of the ubiquinones relies on two new conjunctive reagents, or "linchpins", each of which ultimately corresponds to two or three prenyl units. These allow for attachment of a polyprenyl halide at one end, followed by a Ni(0)-catalyzed cross-coupling at the other terminus with a chloromethylated p-quinone.