2349-58-8

Basic information

• Product Name: 4,5-DIPHENYL-2-IMIDAZOLETHIOL
• Synonyms: 4,5-DIPHENYL-1H-IMIDAZOLE-2-THIOL;4,5-DIPHENYL-2-IMIDAZOLETHIOL;4,5-DIPHENYL-1H-IMIDAZOL-2-YLHYDROSULFIDE;TIMTEC-BB SBB000919;1,3-dihydro-4,5-diphenyl-2H-imidazole-2-thione;4,5-Diphenyl-2-imidazolethiol, HPLC 97%;4,5-DIPHENYL-2-IMIDAZOLETHIOL 97%;4,5-Diphenyl-4-imidazoline-2-thione
• CAS NO: 2349-58-8
• Molecular Formula: C₁₅H₁₂N₂S
• Molecular Weight: 252.33
• EINECS: 219-077-9
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Imidazoles
• Mol File: 2349-58-8.mol
• Article Data: 15

Chemical Properties

• Melting Point: >300 °C(lit.)
• Boiling Point: 407.5°Cat760mmHg
• Flash Point: 200.3°C
• Appearance: /
• Density: 1.1917 (rough estimate)
• Vapor Pressure: 7.51E-07mmHg at 25°C
• Refractive Index: 1.6000 (estimate)
• PKA: 10.17±0.70(Predicted)
• BRN: 187613
• CAS DataBase Reference: 4,5-DIPHENYL-2-IMIDAZOLETHIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DIPHENYL-2-IMIDAZOLETHIOL(2349-58-8)
• EPA Substance Registry System: 4,5-DIPHENYL-2-IMIDAZOLETHIOL(2349-58-8)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 2349-58-8(Hazardous Substances Data)

Usage

Description

4,5-Diphenyl-2-imidazolethiol is a white to light yellow fine crystalline powder with unique chemical properties. It is a compound that has potential applications in various fields due to its specific characteristics.

Uses

Used in Chemical Synthesis Studies:
4,5-Diphenyl-2-imidazolethiol is used as a chemical intermediate for the synthesis of various organic compounds. Its unique structure allows it to be a valuable building block in the development of new molecules with specific properties and applications.
Used in Pharmaceutical Industry:
4,5-Diphenyl-2-imidazolethiol is used as a key component in the development of pharmaceuticals, particularly in the synthesis of drugs targeting specific biological pathways. Its chemical properties make it a promising candidate for the creation of novel therapeutic agents.
Used in Material Science:
In the field of material science, 4,5-diphenyl-2-imidazolethiol is used as a component in the development of advanced materials with specific properties, such as improved stability, reactivity, or selectivity. Its unique structure contributes to the overall performance of these materials.
Used in Research and Development:
4,5-Diphenyl-2-imidazolethiol is used as a research tool in various scientific studies, including the investigation of its chemical properties, reactivity, and potential applications in different industries. It serves as a valuable compound for understanding the underlying principles of chemical reactions and interactions.

InChI:InChI=1/C15H12N2S/c18-15-16-13(11-7-3-1-4-8-11)14(17-15)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18)

Upstream product

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 17356-08-0 thiourea 
• 1147550-11-5 ammonium thiocyanate 
• 16099-67-5 4,5-diphenylimidazolidine-2-thione 
• 100-52-7 benzaldehyde 

Downstream Products

• 180904-58-9 (4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-acetic acid [2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazide 
• 1027262-87-8 (4,5-diphenyl-1H-imidazol-2-ylsulfanyl)-acetic acid (5-methyl-2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazide 
• 180904-63-6 (4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-acetic acid [5-bromo-2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazide 
• 1026985-69-2 (4,5-diphenyl-1H-imidazol-2-ylsulfanyl)-acetic acid (5-chloro-2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazide 
• 161669-77-8 N-<5-<(4,5-diphenyl-1H-imidazol-2-yl)thio>pentyl>-2,4,6-trufluorophenylamine 

Relevant articles and documents

Regio- and stereoselective synthesis of thioglycosides from 4,5-diphenyl- and 3,4,5-triphenylimidazole-2-thione

Six new thioglycosides incorporating the 4,5-diphenyl- and 3,4,5-triphenylimidazole moiety have been successfully synthesized under both conventional and microwave conditions by reaction of the corresponding thiones with aceto-bromosugars in presence of t

Efficient Green Synthesis and Computational Chemical Study of Some Interesting Heterocyclic Derivatives as Insecticidal Agents

A series of 5,5-diarylhydantoin (Dilantin) 3, 4, and 7, imidazole 1, 2, 5, 6, 8, and 9, thiazole 10–12, triazinthione 13, 15, 16, and 17, and thiadiazine 14 derivatives, containing diverse hydrophobic groups, were green synthesized through one-pot stepwise reaction of aromatic aldehydes, vitamin B1, and nitrogen nucleophiles, for example, urea, thiourea, and thiosemicarbazide using grinding technique as well as conventional thermal methods. Such synthesized compounds have potent insecticidal activities; for example, compounds 4, 6, and 17 exhibited the highest insecticidal activity against both Plutella xylostella and Helicoverpa armigera with minimum inhibitory concentration values at 500?μg/mL and LD50 activities at 50?μg/mL. The density functional theory was then applied to explore the structural and electronic characteristics of these compounds. All the synthesized compounds have been characterized based on their elemental analyses and spectral data.

Environmentally benign approach to imidazole 2-thiones

An ecofriendly synthesis of some novel 1,4,5-triarylimidazole-2-thiones/l, 3,4,5-tetraarylimidazole-2-thiones is described. The reaction involves condensation of benzoin with various readily accessible N-substituted thioureas/N,N'-disubstituted thioureas under microwave over recyclable inorganic solid support. This methodology eliminates the usage of solvent and external catalyst in the reaction step and reduces the reaction time from hours to minutes along with remarkable yield enhancement. In addition versatility of various solid supports as catalyst is also studied.