2345-24-6

Basic information

• Product Name: NERYL ISOBUTYRATE
• Synonyms: NERYL ISOBUTYRATE;FEMA 2775;(z)-2-methylpropanoicacid3,7-dimethyl-2,6-octadienylester;2-methyl-,3,7-dimethyl-2,6-octadienylester,(z)-propanoicaci;2-methyl-,3,7-dimethyl-2,6-octadienylester,(Z)-Propanoicacid;3,7-dimethyl-2,6-octadienylester,(z)-isobutyricaci;cis-3,7-dimethyl-2,6-octadien-1-ylisobutyrate;NERY ISO BUTYRATE
• CAS NO: 2345-24-6
• Molecular Formula: C₁₄H₂₄O₂
• Molecular Weight: 224.34
• EINECS: 219-061-1
• Product Categories: Alphabetical Listings;Flavors and Fragrances;M-N
• Mol File: 2345-24-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 229 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 0.895 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00157mmHg at 25°C
• Refractive Index: n20/D 1.457(lit.)
• CAS DataBase Reference: NERYL ISOBUTYRATE(CAS DataBase Reference)
• NIST Chemistry Reference: NERYL ISOBUTYRATE(2345-24-6)
• EPA Substance Registry System: NERYL ISOBUTYRATE(2345-24-6)

Safety Data

• WGK Germany: 2
• RTECS: UA2468500
• Hazardous Substances Data: 2345-24-6(Hazardous Substances Data)

Usage

Description

Neryl isobutyrate is an organic compound that has been reported in the essential oils of plants such as Artemisia absinthium L. and Telekia speciosa (Schreb.) Baumg. It has a delicate, sweet, rose-like fragrance with a slightly fruity undertone and a sweet, strawberry taste. It can be prepared by esterification of nerol using isobutyric acid or the anhydride.

Uses

Used in Flavor Industry:
Neryl isobutyrate is used as a flavoring agent for its sweet, fruity, and slightly waxy taste. It is often used to enhance the flavor of various food and beverage products.
Used in Fragrance Industry:
Neryl isobutyrate is used as a fragrance ingredient for its delicate, sweet, rose-like fragrance with a slightly fruity undertone. It is commonly used in the production of perfumes, colognes, and other scented products.
Used in Essential Oils Industry:
Neryl isobutyrate is used in the essential oils industry as it has been reported found in the essential oils of plants such as Artemisia absinthium L. and Telekia speciosa (Schreb.) Baumg. It adds a unique and pleasant aroma to these essential oils, which can be used in aromatherapy and other applications.
Used in Cosmetics Industry:
Neryl isobutyrate is used in the cosmetics industry for its pleasant fragrance and taste. It can be added to various cosmetic products such as lotions, creams, and perfumes to enhance their sensory appeal.
Used in Aromatherapy:
Neryl isobutyrate is used in aromatherapy for its calming and uplifting properties. Its sweet, rose-like fragrance can help create a relaxing and soothing atmosphere, making it a popular choice for aromatherapy practitioners.
Used in the Production of Natural Flavors and Fragrances:
Neryl isobutyrate is used in the production of natural flavors and fragrances due to its unique and pleasant aroma. It can be used as a natural alternative to synthetic fragrances and flavorings in various applications.

Preparation

By esterification of nerol using isobutyric acid or the anhydride

InChI:InChI=1/C14H24O2/c1-11(2)7-6-8-13(5)9-10-16-14(15)12(3)4/h7,9,12H,6,8,10H2,1-5H3/b13-9+

Upstream product

• 106-24-1 Geraniol 
• 79-30-1 isobutyryl chloride 
• 97-62-1 Ethyl isobutyrate 
• 79-31-2 isobutyric Acid 
• 7137-29-3 isobutyric acetic anhydride 
• 106-25-2 Nerol 

Relevant articles and documents

New neryl esters from Helichrysum italicum (Roth) G. Don (Asteraceae) essential oil

Helichrysum italicum (immortelle) is a dwarf aromatic shrub native to the Mediterranean region. The typical subspecies (italicum) produces an essential oil rich in neryl acetate and characteristic β-diketones, italidiones, highly valued in the perfume industry. As esters are an important group of aroma-active volatiles, herein the composition of the ester fraction of this immortelle chemotype essential oil was studied in detail. Chromatographic separation of Corsican immortelle essential oil enabled the discovery of numerous potentially olfactory-interesting esters of nerol and/or angelic acid, undetectable by direct GC-MS analyses of the unfractioned oil. Four esters of nerol and medium-chain branched fatty acids represent new natural products, while several other esters have a rather restricted occurrence in the Plant Kingdom.

Tyrosinase inhibitors

Methods and compositions are provided for inhibiting the activity of tyrosinase in a host and, as a result, inhibiting melanin-formation. The tyrosinase-inhibitor active ingredient is a compound or mixture of compounds represented by the following structural formulae (I) and (II): STR1 wherein the dotted lines at a, b, c, d, e, f, g, represent an optional double bond, provided that double bonds are not at both b and c, or at both f and g, at the same time; R1, R5, R6, and R7 are each hydrogen or methyl; R2 and R8 are each no group, or each hydrogen or hydroxyl when there is no double bond at a and at f, respectively; R3 is methylene when there is a double bond at b, or hydrogen or methyl when there is no double bond at b; R4 is formyl or --(CH2)n --R10, wherein R10 is hydrogen, hydroxyl, acyloxy, or cyano and n is an integer of from 1 to 3; and R9 is methylene when there is a double bond at g, or --(CH2)n --R10 when there is no double bond at g.

Synthesis of Terpene Alcohol Esters by Lipase

-